ROS-responsive polyurethane fibrous patches loaded with methylprednisolone (MP) for restoring structures and functions of infarcted myocardium in vivo
Y Yao, J Ding, Z Wang, H Zhang, J Xie, Y Wang… - Biomaterials, 2020 - Elsevier
Reactive oxygen species (ROS) play an important role in the pathogenesis of numerous
diseases including atherosclerosis, diabetes, inflammation and myocardial infarction (MI). In …
diseases including atherosclerosis, diabetes, inflammation and myocardial infarction (MI). In …
Alleviating oxidative injury of myocardial infarction by a fibrous polyurethane patch with condensed ROS‐scavenging backbone units
Excessive reactive oxygen species (ROS) generated after myocardial infarction (MI) result in
the oxidative injury in myocardium. Implantation of antioxidant biomaterials, without the use …
the oxidative injury in myocardium. Implantation of antioxidant biomaterials, without the use …
Engineering bioinspired antioxidant materials promoting cardiomyocyte functionality and maturation for tissue engineering application
Oxidative stress plays an important role in various pathological conditions, such as wound
healing, inflammation, myocardial infarction, and biocompatibility of the materials …
healing, inflammation, myocardial infarction, and biocompatibility of the materials …
Multifunctional elastomer cardiac patches for preventing left ventricle remodeling after myocardial infarction in vivo
Myocardial infarction (MI) is still a major cause of mortality and morbidity worldwide.
Elastomer cardiac patches have shown great potential in preventing left ventricle (LV) …
Elastomer cardiac patches have shown great potential in preventing left ventricle (LV) …
Synthesis, characterization and antioxidant activity of a novel electroactive and biodegradable polyurethane for cardiac tissue engineering application
There has been a growing trend towards applying conducting polymers for electrically
excitable cells to increase electrical signal propagation within the cell-loaded substrates. A …
excitable cells to increase electrical signal propagation within the cell-loaded substrates. A …
An elastic, biodegradable cardiac patch induces contractile smooth muscle and improves cardiac remodeling and function in subacute myocardial infarction
KL Fujimoto, K Tobita, WD Merryman, J Guan… - Journal of the American …, 2007 - jacc.org
Objectives: Our objective in this study was to apply an elastic, biodegradable polyester
urethane urea (PEUU) cardiac patch onto subacute infarcts and to examine the resulting …
urethane urea (PEUU) cardiac patch onto subacute infarcts and to examine the resulting …
Bi-layered polyurethane–extracellular matrix cardiac patch improves ischemic ventricular wall remodeling in a rat model
As an intervention to abrogate ischemic cardiomyopathy, the concept of applying a
temporary, local patch to the surface of the recently infarcted ventricle has been explored …
temporary, local patch to the surface of the recently infarcted ventricle has been explored …
In vivo self-assembled shape-memory polyurethane for minimally invasive delivery and therapy
S Li, H Zhang, J Xie, Z Wang, K Wang, Z Zhai… - Materials …, 2023 - pubs.rsc.org
Advanced elastomers are highly in demand for the fabrication of medical devices for
minimally invasive surgery (MIS). Herein, a shape memory and self-healing polyurethane …
minimally invasive surgery (MIS). Herein, a shape memory and self-healing polyurethane …
Oxygen releasing and antioxidant breathing cardiac patch delivering exosomes promotes heart repair after myocardial infarction
Constant oxygen supply is inevitable for cardiac tissue function and survival. Myocardial
infarction (MI) leaves heart tissue in a state of oxygen deficiency, causing oxidative stress …
infarction (MI) leaves heart tissue in a state of oxygen deficiency, causing oxidative stress …
[HTML][HTML] Ameliorating impaired cardiac function in myocardial infarction using exosome-loaded gallic-acid-containing polyurethane scaffolds
Myocardial infarction (MI) can be tackled by implanting cardiac patches which provide
mechanical support to the heart. However, most tissue-engineered scaffolds face difficulty in …
mechanical support to the heart. However, most tissue-engineered scaffolds face difficulty in …