The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to
damage from various factors such as viral infections, drug reactions, excessive alcohol …

Acetaminophen (APAP) is a widely used analgesic and antipyretic over-the-counter
medicine worldwide. Hepatotoxicity caused by APAP overdose is one of the leading causes …

Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …

Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury
worldwide, and mitochondrial oxidative stress is considered the major event responsible for …

Acetaminophen (APAP), which is also known as paracetamol or N-acetyl-p-aminophenol is
a safe and potent drug for fever, pain and inflammation when used at its normal therapeutic …

Liver injury and acute liver failure caused by acetaminophen (APAP, N-acetyl-p-
aminophenol, paracetamol) overdose is a significant clinical problem in most western …

Acetaminophen (APAP) overdose is one of the most common causes of acute liver injury.
The current standard-of-care treatment for APAP hepatotoxicity, N-acetyl-l-cysteine, is highly …

Context Acetaminophen (APAP), also known as paracetamol and N-acetyl p-aminophenol,
is one of the most frequently used drugs for analgesic and antipyretic purposes on a …

Acetaminophen (APAP), one of the most widely used antipyretic and analgesic drugs,
principally contributes to drug-induced liver injury when taken at a high dose. APAP-induced …

The sterile inflammatory response observed after hepatic necrosis caused by an
acetaminophen (APAP) overdose has been a controversial topic for years. In a recent …