Acetaminophen (APAP) toxicity leads to severe acute liver injury (ALI) by inducing excessive
oxidative stress, inflammatory response, and hepatocyte apoptosis. Imperatorin (IMP) is a …

The harm of nonalcoholic fatty liver disease to human health is increasing, which calls for
urgent prevention and treatment of the disease. Isoorientin is an effective ingredient of …

Isoorientin (Iso), a natural bioactive flavonoid, possesses significant anti-tumor and anti-
oxidant activities. Benzo [a] pyrene (BaP) is a food processing injurant with carcinogenicity …

Acetaminophen (APAP) overdose-induced acute liver damage is mostly due to
overwhelmingly increased oxidative stress. Nuclear factor-erythroid 2-related factor2 (Nrf2) …

Excess acetaminophen (APAP) commonly causes severe acute liver injury (ALI),
characterized by oxidative stress, pro-inflammatory responses, and hepatocyte damage …

Acetaminophen (APAP) overdose leads to liver injury. NLRP3 inflammasome is a key player
in APAP‐induced inflammation. Also, apoptosis and liver regeneration play an important …

Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …

Abstract Background Tanshinone IIA (Tan), the main active component of Salvia miltiorrhiza,
has been demonstrated to have antioxidant activity. Acetaminophen (APAP), a widely used …

Cardamonin (CD), a naturally occurring chalcone derived from the Alpinia species, has
been shown to exert antioxidant and anti-inflammatory activity, but its role in the prevention …

Isoorientin (ISO) is a flavonoid compound that can be extracted from several plant species,
such as Phyllostachys pubescens, Patrinia, and Drosophyllum lusitanicum; however, its …