Background/Aims: Pterostilbene (Pts), a natural dimethylated analog of resveratrol from
blueberries, exerts antioxidative and anti-apoptotic effects in various diseases. This study …

Acrylamide (AA) in heat-processed food leads to widespread concerns due to its
hepatotoxicity. Allicin, a plant-derived antioxidant, possesses a significant protective effect …

Objectives Acetaminophen (APAP) overdose has been the primary cause of drug-induced
liver injury (DILI) in western countries. Monoammonium glycyrrhizinate (MG) is a primary …

Isoorientin (ISO) is considered one of the most important flavonoid-like compounds
responsible for health benefits, including the prevention of liver damage as well as …

Acetaminophen (APAP) overdose is one of the most common causes of drug-induced acute
liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) …

Background Limonin, a bioactive compound from citrus plants, exerts antioxidant activities,
however its therapeutic potential in acetaminophen (APAP)-induced hepatotoxicity remains …

Acetaminophen (N-acetyl p-aminophenol or APAP) is used worldwide for its antipyretic and
anti-inflammatory potential. However, APAP overdose sometimes causes severe liver …

Puerarin (Pue) is a kind of isoflavone compound extracted from Pueraria lobata, which has
significant antioxidant activity. Excessive use of acetaminophen (APAP) can cause oxidative …

Ethnopharmacological relevance Oroxyloside is a natural flavonoid isolated from Scutellaria
baicalensis Georgi (Lamiaceae) which is a Chinese herb widely used for liver diseases …

Oxidative stress plays a crucial role in the pathogenesis of acute pancreatitis (AP).
Isoliquiritigenin (ISL) is a flavonoid monomer with confirmed antioxidant activity. However …