The current status of glucocorticoid alterations in post‐traumatic stress disorder (PTSD) will
be described in this chapter. Emphasis will be placed on data that suggest that at least some …

The findings from investigations of the neuroendocrinology of posttraumatic stress disorder
(PTSD) have highlighted alterations that have not historically been associated with …

OBJECTIVE: Previous theories have emphasized the role of excessive glucocorticoid activity
in the pathology of chronic stress. Nevertheless, insufficient glucocorticoid signaling …

It has been hypothesized that stress damages the hippocampus and results in myriad other
deleterious consequences owing to the toxic effects of cortisol, presumed to be released in …

Epidemiological data have linked an adverse fetal environment with increased risks of
cardiovascular, metabolic, neuroendocrine, and psychiatric disorders in adulthood. Prenatal …

This review examines the putative link between glucocorticoid and hippocampal
abnormalities in posttraumatic stress disorder (PTSD). Increased glucocorticoid receptor …

Patients with critical illness who are treated in an intensive care unit (ICU) often report
traumatic memories from ICU treatment, receive exogenously administered glucocorticoids …

Highlights•Low cortisol, enhanced GR function and a pro-inflammatory state have been
repeatedly observed in subpopulations of PTSD patients.•Biological dysregulation may …

This article reviews memory-related impairments in trauma survivors with posttraumatic
stress disorder and their possible association to neuroendocrine alterations seen in this …

Intergenerational effects of trauma have been observed clinically in a wide range of
populations, and parental PTSD has been associated with an increased risk for …