The clinicopathological features of patients with membranous nephropathy

H Zhu, Q Han, D Zhang, Y Wang, J Gao… - … of Nephrology and …, 2018 - Taylor & Francis
Background Membranous nephropathy (MN) represents a distinct glomerular disease which
has been considered as a major cause of nephrotic syndrome (NS) in adults. Evidences …

A cohort study of membranous nephropathy, primary or secondary

M Arghiani, BH Zamani, F Nazemian, S Samadi… - BMC nephrology, 2021 - Springer
Abstract Background Although IgG4 deposit against phospholipase A2 receptor (anti-
PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous …

Revisiting immunological and clinical aspects of membranous nephropathy

I Nieto-Gañán, I Iturrieta-Zuazo, C Rita… - Clinical …, 2022 - Elsevier
Idiopathic or primary membranous nephropathy (IMN) is one of the most frequent causes of
nephrotic syndrome in adults and the elderly. It is characterized by a thickening of the wall of …

Circulating antibodies against M-type phospholipase A2 receptor and thrombospondin type-1 domain-containing 7A in Chinese patients with membranous …

C Tian, L Li, T Liu, X Qu, Y Qiu - International Urology and Nephrology, 2019 - Springer
Background M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1
domain-containing 7A (THSD7A) have recently been identified as target antigens for …

Prognostic value of PLA2R autoimmunity detected by measurement of anti-PLA2R antibodies combined with detection of PLA2R antigen in membranous nephropathy …

F Pourcine, K Dahan, F Mihout, M Cachanado… - PloS one, 2017 - journals.plos.org
Introduction Clinical course of membranous nephropathy (MN) is difficult to predict.
Measurement of circulating anti-PLA2R autoantibodies (PLA2R-Ab) and detection in …

Strong Association of Idiopathic Membranous Nephropathy (IMN) with HLA‐DR 3 and MT‐2 without Involvement of HLA‐B 18 and no Association to BfF1

GA Müller, C Müller, G Liebau, J Kömpf, H Ising… - Tissue …, 1981 - Wiley Online Library
The present study investigated the distribution of HLA‐antigens and Bf alleles in a group of
21 patients suffering from biopsy proven Idiopathic Membranous Nephropathy (IMN). A …

Anti-phospholipase A2 receptor antibodies and the pathogenesis of membranous nephropathy

P Ronco, H Debiec - Nephron Clinical Practice, 2015 - karger.com
Since the early 2000s, considerable advances have been achieved in the understanding of
molecular pathomechanisms of human membranous nephropathy (MN), inspired by studies …

Role of phospholipase A2 receptor 1 antibody level at diagnosis for long-term renal outcome in membranous nephropathy

M Mahmud, HO Pinnschmidt, L Reinhard… - PLoS …, 2019 - journals.plos.org
Background Membranous nephropathy (MN) is an autoimmune disease induced by
circulating antibodies against the podocyte protein phospholipase A2 receptor 1 (PLA2R1 …

The Role of Anti-PLA2R and Anti-THSD7A Antibodies in the Pathogenesis and Diagnostics of Primary Membranous Nephropathy: A Review of Current Knowledge …

I Smarz-Widelska, D Chojęta, MM Kozioł - International Journal of …, 2022 - mdpi.com
Primary membranous nephropathy (PMN) is considered a major cause of nephrotic
syndrome. The discovery of circulating autoantibodies directed against glomerular …

Response to immunosuppressive therapy in PLA2R- associated and non-PLA2R- associated idiopathic membranous nephropathy: a retrospective, multicenter …

J Wang, Q Xie, Z Sun, N Xu, Y Li, L Wang, S Liu, J Xue… - BMC nephrology, 2017 - Springer
Background According to renal M type phospholipase A 2 receptor (PLA 2 R)
immunohistochemistry, idiopathic membranous nephropathy (IMN) could be categorized …