A proposal for a serology-based approach to membranous nephropathy

AS De Vriese, RJ Glassock, KA Nath… - Journal of the …, 2017 - journals.lww.com
Primary membranous nephropathy (MN) is an autoimmune disease mainly caused by
autoantibodies against the recently discovered podocyte antigens: the M-type …

[HTML][HTML] Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the main cause of adult nephrotic syndrome (NS). The
pathogenesis of MN is complex and involves subepithelial immune complex deposition …

Management of patients with membranous nephropathy

JM Hofstra, JFM Wetzels - Nephrology Dialysis Transplantation, 2012 - academic.oup.com
Membranous nephropathy (MN) is the most common cause of the nephrotic syndrome in
Europe, with an incidence of 5–10/million/year in adults [1]. Although MN can occur …

[HTML][HTML] Primary membranous glomerulonephritis: the role of serum and urine biomarkers in patient management

SM Maifata, R Hod, F Zakaria, FA Ghani - Biomedicines, 2019 - mdpi.com
The detection of phospholipase A2 receptor (PLA2R) and thrombospondin domain
containing 7A THSD7A among primary membranous glomerulonephritis (MGN) patients …

HLA-D and PLA2R1 risk alleles associate with recurrent primary membranous nephropathy in kidney transplant recipients

L Berchtold, E Letouzé, MP Alexander, G Canaud… - Kidney international, 2021 - Elsevier
Recurrence of primary membranous nephropathy after transplantation occurs in up to 44%
of patients and is driven by PLA2R antibody. Here, we asked whether genetic determinants …

[HTML][HTML] TNFA2 and d2 alleles of the tumor necrosis factor alpha gene polymorphism are associated with onset/occurrence of idiopathic membranous nephropathy

D Thibaudin, L Thibaudin, P Berthoux, C Mariat… - Kidney international, 2007 - Elsevier
Idiopathic membranous nephropathy (IMN) has a strong association with the major
histocompatibility complex HLA B8DR3 (17) DQ2 haplotype. The tumor necrosis factor (TNF) …

Increasing prevalence of membranous nephropathy in patients with primary glomerular diseases: A cross‐sectional study in China

L Tang, J Yao, X Kong, Q Sun, Z Wang, Y Zhang… - …, 2017 - Wiley Online Library
Aim Primary glomerular disease (PGD) remains the most common renal disease in China. A
limited number of single centre studies show that the frequency of membranous …

[HTML][HTML] New antigens involved in membranous nephropathy beyond phospholipase A2 receptor

M Salvadori, A Tsalouchos - World Journal of Nephrology, 2022 - ncbi.nlm.nih.gov
When the physiopathology of membranous nephropathy was first described, almost 30% of
cases were recognized to be secondary to well-known diseases such as autoimmune …

[HTML][HTML] Biomarkers to detect membranous nephropathy in Chinese patients

L Lin, WM Wang, XX Pan, J Xu, CN Gao, W Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Anti-M-type phospholipase A 2 receptor (anti-PLA 2 R) is a widely accepted biomarker for
clinical idiopathic membranous neurophathy (IMN). However, its ability to differentiate …

[HTML][HTML] Relationship between renal tissues phospholipase A2 receptor and its serum antibody and clinical condition and prognosis of idiopathic membranous …

D Dong, T Fan, Y Wang, L Zhang, L Song, L Zhang - BMC nephrology, 2019 - Springer
Objective To investigate the correlation of M-type phospholipase A2 receptor (PLA2R)
expression and serum anti-PLA2R antibody with the clinical parameters and prognosis of …