Longitudinal cytokine profile in patients with mild to critical COVID-19
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …
Tocilizumab for severe worsening COVID-19 pneumonia: a propensity score analysis
M Roumier, R Paule, A Vallée, J Rohmer… - Journal of clinical …, 2021 - Springer
Background High levels of serum interleukin-6 (IL-6) correlate with disease severity in
COVID-19. We hypothesized that tocilizumab (a recombinant humanized anti-IL-6 receptor) …
COVID-19. We hypothesized that tocilizumab (a recombinant humanized anti-IL-6 receptor) …
Validation of predictors of disease severity and outcomes in COVID-19 patients: a descriptive and retrospective study
L Tan, X Kang, X Ji, G Li, Q Wang, Y Li, Q Wang… - Med, 2020 - cell.com
Background The severity and outcome of COVID-19 cases has been associated with the
percentage of circulating lymphocytes (LYM%), levels of C-reactive protein (CRP) …
percentage of circulating lymphocytes (LYM%), levels of C-reactive protein (CRP) …
Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study
SK Byeon, AK Madugundu, K Garapati… - The Lancet Digital …, 2022 - thelancet.com
Background COVID-19 is a multi-system disorder with high variability in clinical outcomes
among patients who are admitted to hospital. Although some cytokines such as interleukin …
among patients who are admitted to hospital. Although some cytokines such as interleukin …
Prognostic value of interleukin-18 and its association with other inflammatory markers and disease severity in COVID-19
H Satış, HS Özger, PA Yıldız, K Hızel, Ö Gulbahar… - Cytokine, 2021 - Elsevier
Background The effectual immune response is crucial to defeat viral infections. However,
exuberant immune response with features of macrophage activation syndrome (MAS) lead …
exuberant immune response with features of macrophage activation syndrome (MAS) lead …
IL-6–based mortality risk model for hospitalized patients with COVID-19
R Laguna-Goya, A Utrero-Rico, P Talayero… - Journal of Allergy and …, 2020 - Elsevier
Background Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic.
Because the severity of the disease is highly variable, predictive models to stratify patients …
Because the severity of the disease is highly variable, predictive models to stratify patients …
Role of interleukin 6 as a predictive factor for a severe course of Covid-19: retrospective data analysis of patients from a long-term care facility during Covid-19 …
P Sabaka, A Koščálová, I Straka, J Hodosy… - BMC infectious …, 2021 - Springer
Background Covid-19 is a disease with high morbidity and mortality among elderly residents
of long-term care facilities (LTCF). During an outbreak of SARS-CoV-2 infection in the LTCF …
of long-term care facilities (LTCF). During an outbreak of SARS-CoV-2 infection in the LTCF …
Serum IL-23, IL-10, and TNF-α predict in-hospital mortality in COVID-19 patients
Objective The hyperinflammatory response, caused by severe acute respiratory syndrome-2
(SARS-CoV-2), is the most common cause of death in patients with coronavirus disease …
(SARS-CoV-2), is the most common cause of death in patients with coronavirus disease …
Elevated interleukin levels are associated with higher severity and mortality in COVID 19–a systematic review, meta-analysis, and meta-regression
Background and aims COVID 19 pneumonia commonly leads to ARDS. The occurrence of
ARDS in COVID 19 patients is thought to occur secondary to an exaggerated immunologic …
ARDS in COVID 19 patients is thought to occur secondary to an exaggerated immunologic …
Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19
F Liu, L Li, MD Xu, J Wu, D Luo, YS Zhu, BX Li… - Journal of clinical …, 2020 - Elsevier
Background The inflammatory response plays a critical role in coronavirus disease 2019
(COVID-19), and inflammatory cytokine storm increases the severity of COVID-19. Objective …
(COVID-19), and inflammatory cytokine storm increases the severity of COVID-19. Objective …