Maternal care of pups influences the development of hypothalamic–pituitary–adrenal (HPA)
responses to stress in the rat. Thus, the adult offspring of mothers which naturally show an …

Increased levels of pup licking/grooming and arched-back nursing by rat mothers over the
first week of life alter the epigenome at a glucocorticoid receptor gene promoter in the …

Here we report that increased pup licking and grooming (LG) and arched-back nursing
(ABN) by rat mothers altered the offspring epigenome at a glucocorticoid receptor (GR) gene …

Background: In animal models, variations in early maternal care are associated with
differences in hypothalamic-pituitary-adrenal (HPA) stress response in the offspring …

Early experience permanently alters behavior and physiology. These effects are, in part,
mediated by sustained alterations in gene expression in selected brain regions. The critical …

The early nurturing environment has persistent influences on developmental programming
of inter-individual differences in metabolic and endocrine function that contribute to …

The nature of maternal care that an infant receives can effect the child's emotional and
cognitive development, which is endured into adulthood. Similarly, maternal behavior in …

Exposure to stress during early development causes long‐lasting alterations in behaviour
and hypothalamic pituitary adrenal (HPA) axis activity, including increased expression of …

Parental care influences development across mammals. In humans such influences include
effects on phenotypes, such as stress reactivity, which determine individual differences in …

Epidemiological data indicate that an adverse maternal environment during pregnancy
predisposes offspring to metabolic syndrome with increased obesity, and type 2 diabetes …