Background Chloride administration has been found to be harmful to the kidney in critically
ill patients. However the association between plasma chloride concentration and renal …

Background Chloride‐rich fluids have been found to associate with an increased risk for
acute kidney injury (AKI) among intensive care unit (ICU) patients. Studies evaluating the …

Purpose The aim of this study was to determine whether serum chloride and changes in
serum chloride over time were associated with acute kidney injury (AKI) or intensive care …

Background Hyperchloremia is common in critically ill septic patients. The impact of
hyperchloremia on the incidence of acute kidney injury (AKI) is not well studied. We …

Chloride is the principal anion of the extracellular fluid and vital for both serum
electroneutrality and acid-base homeostasis. The aim of this review is to investigate the …

Acute kidney injury (AKI) is a major public health problem that complicates 10–40% of
hospital admissions. Importantly, AKI is independently associated with increased risk of …

Results A total of 1321 patients were evaluated for inclusion and 410 patients met the study
inclusion criteria (209 high-chloride group and 201 low-chloride group). Primary reasons for …

The aim of this observational retrospective cohort study was to analyze the association
between hyperchloremia and serum chloride variation with in-hospital acute kidney injury …

Background Abnormal chloride levels are commonly observed in critically ill patients, but
their clinical relevance remains a matter of debate. We examined the association between …

Background Whether perioperative hyperchloremia can induce postoperative acute kidney
injury (AKI) is controversial. We investigated the association between perioperative …