Controlled studies have shown that monitoring of the exhaled nitric oxide fraction (F eNO)
improves asthma management. However, the studies seldom consider the full range of …

The clinical value of measuring fractional exhaled nitric oxide (F eNO) in asthma is not clear.
We aimed to assess whether F eNO can reliably predict clinical outcomes in asthma treated …

Background: Asthma guidelines emphasize maintaining disease control. However, objective
measures of asthma disease control are lacking. Objective: We sought to examine the …

Background: Exhaled nitric oxide (FE NO) measurements may help to highlight when
inhaled corticosteroid (ICS) therapy should or should not be adjusted in asthma. This is often …

BACKGROUND Patients with difficult asthma suffer chronic moderate to severe persistent
asthma symptoms despite high doses of inhaled and oral corticosteroid therapy. These …

BACKGROUND: Bronchial reactivity and exhaled nitric oxide (eNO) are not often used to
monitor control and severity of asthma in clinical practice. OBJECTIVE: To evaluate the …

Rationale: Current asthma guidelines recommend adjusting antiinflammatory treatment on
the basis of the results of lung function tests and symptom assessment, neither of which are …

A major goal of asthma management is maintaining optimal control. Current assessment is
based on symptoms and lung function. We evaluated whether domiciliary daily home …

Objective: Exhaled nitric oxide (eNO) has been used as a surrogate of airway inflammation
in mild asthma. However, whether eNO levels reflect disease activity in symptomatic …

We aimed to evaluate the accuracy of baseline exhaled nitric oxide fraction (F eNO) to
recognise individuals with difficult-to-treat asthma who have the potential to achieve control …