Disarming Fungal Pathogens: Bacillus safensis Inhibits Virulence Factor Production and Biofilm Formation by Cryptococcus neoformans and Candida albicans

FL Mayer, JW Kronstad - MBio, 2017 - Am Soc Microbiol
Bacteria interact with each other in nature and often compete for limited nutrient and space
resources. However, it is largely unknown whether and how bacteria also interact with …

Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses

CR Hole, WC Lam, R Upadhya, JK Lodge - MBio, 2020 - Am Soc Microbiol
Cryptococcus neoformans infections are significant causes of morbidity and mortality among
AIDS patients and the third most common invasive fungal infection in organ transplant …

Virulence and biofilms as promising targets in developing antipathogenic drugs against candidiasis

MS Ahmad Khan, F Alshehrei, SB Al-Ghamdi… - Future science …, 2020 - Taylor & Francis
Candida albicans has remained the main etiological agent of candidiasis, challenges
clinicians with high mortality and morbidity. The emergence of resistance to antifungal drugs …

Commensal protection of Staphylococcus aureus against antimicrobials by Candida albicans biofilm matrix

EF Kong, C Tsui, S Kucharíková, D Andes, P Van Dijck… - MBio, 2016 - Am Soc Microbiol
Biofilm-associated polymicrobial infections, particularly those involving fungi and bacteria,
are responsible for significant morbidity and mortality and tend to be challenging to treat …

Biofilm Formation by the Fungal PathogenCandida albicans: Development, Architecture, and Drug Resistance

J Chandra, DM Kuhn, PK Mukherjee… - Journal of …, 2001 - Am Soc Microbiol
Biofilms are a protected niche for microorganisms, where they are safe from antibiotic
treatment and can create a source of persistent infection. Using two clinically relevant …

High-content phenotypic screenings to identify inhibitors of Candida albicans biofilm formation and filamentation

CG Pierce, SP Saville, JL Lopez-Ribot - Pathogens and disease, 2014 - academic.oup.com
Candida species represent the main cause of opportunistic fungal infections worldwide, and
Candida albicans remains the most common etiological agent of candidiasis, now the third …

Transcriptomic and Genomic Approaches for Unravelling Candida albicans Biofilm Formation and Drug Resistance—An Update

PP Chong, VK Chin, WF Wong, P Madhavan, VC Yong… - Genes, 2018 - mdpi.com
Candida albicans is an opportunistic fungal pathogen, which causes a plethora of
superficial, as well as invasive, infections in humans. The ability of this fungus in switching …

Cryptococcus neoformans Biofilm Formation Depends on Surface Support and Carbon Source and Reduces Fungal Cell Susceptibility to Heat, Cold, and UV Light

LR Martinez, A Casadevall - Applied and environmental …, 2007 - Am Soc Microbiol
The fungus Cryptococcus neoformans possesses a polysaccharide capsule and can form
biofilms on medical devices. We describe the characteristics of C. neoformans biofilm …

[HTML][HTML] Microbial competition between Escherichia coli and Candida albicans reveals a soluble fungicidal factor

DJ Cabral, S Penumutchu, C Norris… - Microbial …, 2018 - ncbi.nlm.nih.gov
Localized and systemic fungal infections caused by Candida albicans can lead to significant
mortality and morbidity. However, severe C. albicans infections are relatively rare, occurring …

Candida albicans Biofilms and Human Disease

CJ Nobile, AD Johnson - Annual review of microbiology, 2015 - annualreviews.org
In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …