We previously demonstrated that the N-terminal 1000 amino acid residues of human
apolipoprotein (apo) B (designated apoB: 1000) are competent to fold into a three-sided …

Microsomal triglyceride transfer protein (MTP) is required for the assembly and secretion of
apolipoprotein (apo) B-containing lipoproteins. Previously, we demonstrated that the N …

Cellular apoB in primary rat hepatocyte cultures was pulse-labeled with [35 S] methionine
for 1 h. Cells were then chased with excess unlabeled methionine for periods of up to 16 h in …

The microsomal triglyceride transfer protein (MTP) is a heterodimeric lipid transfer protein
that is required for the assembly and secretion of apolipoprotein B (apoB)-containing …

We studied the role of microsomal triglyceride transfer protein (MTP) in the synthesis,
secretion, and cotranslational degradation of apolipoprotein (apo) B using nonhepatic COS …

Apolipoprotein (apo) B, the major protein component of the atherogenic low-density
lipoprotein (LDL), has a pentapartite structure, NH2-βα1-β1-α2-β2-α3-COOH, the β domains …

The microsomal triglyceride transfer protein (MTP) is required for assembly and secretion of
the lipoproteins containing apolipoprotein B (apoB): very low density lipoproteins and …

To elucidate the role of the microsomal triglyceride transfer protein (MTP) in lipoprotein
assembly, MTP and apolipoprotein B-53 (apoB 53; the N-terminal 53% of apoB) were …

Although microsomal triglyceride transfer protein (MTP) and newly synthesized triglyceride
(TG) are critical for co-translational targeting of apolipoprotein B (apoB100) to lipoprotein …

The microsomal triglyceride transfer protein (MTP) is necessary for the proper assembly of
the apolipoprotein B containing lipoproteins, very low density lipoprotein and chylomicrons …