Weight loss with subcutaneous semaglutide versus other glucagon‐like peptide 1 receptor agonists in type 2 diabetes: a systematic review

B Stretton, J Kovoor, S Bacchi, S Chang… - Internal medicine …, 2023 - Wiley Online Library
Glucagon‐like peptide 1 receptor agonists (GLP‐1 RAs) reduce elevated blood glucose
levels and induce weight loss. Multiple GLP‐1 RAs and one combined GLP‐1/glucose …

A systematic literature review and network meta-analysis comparing once-weekly semaglutide with other GLP-1 receptor agonists in patients with type 2 diabetes …

M Witkowski, L Wilkinson, N Webb, A Weids, D Glah… - Diabetes Therapy, 2018 - Springer
Introduction Once-weekly semaglutide is a glucagon-like peptide-1 (GLP-1) analogue that is
currently available as 1.0 mg and 0.5 mg dose for the treatment of type 2 diabetes (T2D) …

Greater combined reductions in HbA1c≥ 1.0% and weight≥ 5.0% with semaglutide versus comparators in type 2 diabetes

HW Rodbard, S Bellary, I Hramiak, Y Seino, R Silver… - Endocrine Practice, 2019 - Elsevier
Objective: Semaglutide is a glucagon-like peptide 1 (GLP-1) analog for the once-weekly
treatment of type 2 diabetes (T2D). In the global SUSTAIN clinical trial program, semaglutide …

[HTML][HTML] The role of weight control in the management of type 2 diabetes mellitus: Perspectives on semaglutide

P Kurtzhals, FF Kreiner, RS Bindra - Diabetes Research and Clinical …, 2023 - Elsevier
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely used to address multiple
aspects of type 2 diabetes mellitus (T2DM) management, including glycaemic control …

Efficacy and safety of once-weekly semaglutide 2· 4 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double-blind, placebo …

BM McGowan, JM Bruun, M Capehorn… - The Lancet Diabetes & …, 2024 - thelancet.com
Background There are currently limited data regarding the effect of semaglutide 2· 4 mg in
individuals with obesity and prediabetes in clinical trials. We aimed to assess the efficacy …

Semaglutide as a promising antiobesity drug

GA Christou, N Katsiki, J Blundell, G Fruhbeck… - Obesity …, 2019 - Wiley Online Library
Semaglutide is a glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) with a long
elimination half‐life, allowing subcutaneous (sc) administration once per week. Both the …

[HTML][HTML] Efficacy and safety of semaglutide for weight loss in obesity without diabetes: a systematic review and meta-analysis

HC Tan, OA Dampil, MM Marquez - Journal of the ASEAN …, 2022 - ncbi.nlm.nih.gov
Background The weight loss benefit of semaglutide in patients with diabetes is well-
documented, but its clinical utility in treating obesity among patients without diabetes is less …

Once-daily oral semaglutide versus injectable GLP-1 RAs in people with type 2 diabetes inadequately controlled on basal insulin: systematic review and network meta …

B Chubb, P Gupta, J Gupta, S Nuhoho, K Kallenbach… - Diabetes Therapy, 2021 - Springer
Introduction The relative efficacy and safety of once-daily oral semaglutide vs. injectable
glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in subjects with type 2 diabetes …

Orally administered semaglutide versus GLP-1 RAs in patients with type 2 diabetes previously receiving 1–2 oral antidiabetics: systematic review and network meta …

S Nuhoho, J Gupta, BB Hansen, M Fletcher-Louis… - Diabetes Therapy, 2019 - Springer
Introduction Orally administered semaglutide is the first glucagon-like peptide 1 receptor
agonist (GLP-1 RA) for oral administration. As head-to-head trials assessing orally …

Efficacy of semaglutide in overweight and obese patients with type 1 diabetes

SK Garg, G Kaur, Z Haider, E Rodriquez… - Diabetes Technology …, 2024 - liebertpub.com
Introduction: More than two-thirds of patients with type 1 diabetes (T1D) are overweight (OW)
and/or obese (OB) in the USA and Western Europe, resulting in insulin resistance as in type …