Oxidant/antioxidant imbalance and the risk of Alzheimer's disease

AE Abdel Moneim - Current Alzheimer Research, 2015 - ingentaconnect.com
Alzheimer's disease (AD) is the most common form of dementia characterized by
progressive loss of memory and other cognitive functions among older people. Senile …

Role of reactive oxygen species in the progression of Alzheimer's disease

S Bhatt, L Puli, CR Patil - Drug discovery today, 2021 - Elsevier
Highlights•Oxidative stress is an etiopathogenic event upstream to Aβ-plaques and
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …

Oxidative stress in Alzheimer's disease

Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …

Antioxidant treatment in Alzheimer's disease: current state

Y Gilgun-Sherki, E Melamed, D Offen - Journal of Molecular Neuroscience, 2003 - Springer
Accumulating data from experimental and human studies indicate that oxidative stress (OS)
plays a major role in the pathogenesis of Alzheimer's disease (AD). The production of …

Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

Oxidative stress and the pathogenesis of Alzheimer′ s disease

Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …

Antioxidants: An approach for restricting oxidative stress induced neurodegeneration in Alzheimer's disease

S Dubey, E Singh - Inflammopharmacology, 2023 - Springer
Alzheimer's disease (AD) is the leading cause of dementia, affecting millions of people
worldwide. Oxidative stress contributes towards induction of neurodegeneration. It is one of …

Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?

PI Moreira, MA Smith, X Zhu, K Honda… - Drug news & …, 2005 - europepmc.org
Oxidative stress is a key factor involved in the development and progression of Alzheimer's
disease, and it is well documented that free radical oxidative damage, particularly of …

Oxidative stress in Alzheimer's disease: why did antioxidant therapy fail?

T Persson, BO Popescu… - Oxidative medicine and …, 2014 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia in the elderly, with
increasing prevalence and no disease‐modifying treatment available yet. A remarkable …

Antioxidant therapies for Alzheimer′ s disease

Y Feng, X Wang - Oxidative medicine and cellular longevity, 2012 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative disease featuring
progressive impairments in memory, cognition, and behavior and ultimately leads to death …