Anti-inflammatory effects of melatonin in obesity and hypertension

NJ Prado, L Ferder, W Manucha, ER Diez - Current hypertension reports, 2018 - Springer
Abstract Purpose of Review Here, we review the known relations between hypertension and
obesity to inflammation and postulate the endogenous protective effect of melatonin and its …

Dietary melatonin supplementation could be a promising preventing/therapeutic approach for a variety of liver diseases

F Bonomini, E Borsani, G Favero, LF Rodella… - Nutrients, 2018 - mdpi.com
In the therapeutic strategies, the role of diet is a well-established factor that can also have an
important role in liver diseases. Melatonin, identified in animals, has many antioxidant …

Melatonin: facts, extrapolations and clinical trials

JA Boutin, DJ Kennaway, R Jockers - Biomolecules, 2023 - mdpi.com
Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

Melatonin as an anti‐inflammatory agent modulating inflammasome activation

G Favero, L Franceschetti, F Bonomini… - International journal …, 2017 - Wiley Online Library
Inflammation may be defined as the innate response to harmful stimuli such as pathogens,
injury, and metabolic stress; its ultimate function is to restore the physiological homeostatic …

Benefits and adverse events of melatonin use in the elderly

L Anghel, L Baroiu, CR Popazu… - Experimental and …, 2022 - spandidos-publications.com
Melatonin is a hormone secreted by the pineal gland in accordance with the circadian
rhythm when the light level decreases. Reduction of melatonin secretion with age may be …

Utilizing melatonin to combat bacterial infections and septic injury

W Hu, C Deng, Z Ma, D Wang, C Fan… - British journal of …, 2017 - Wiley Online Library
Melatonin, also known as N‐acetyl‐5‐methoxytryptamine, is a ubiquitously acting molecule
that is produced by the pineal gland and other organs of animals, including humans. As …

Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies

M Wilhelmsen, I Amirian, RJ Reiter… - Journal of pineal …, 2011 - Wiley Online Library
Melatonin is an endogenous indoleamine, produced mainly by the pineal gland. Melatonin
has been proven to have chronobiotic, antioxidant, antihypertensive, anxiolytic and sedative …

Melatonin normalizes clinical and biochemical parameters of mild inflammation in diet‐induced metabolic syndrome in rats

P Cano Barquilla, ES Pagano… - Journal of pineal …, 2014 - Wiley Online Library
The objective of this study was to evaluate the efficacy of melatonin to affect mild
inflammation in the metabolic syndrome (MS) induced by a high‐fat diet in rats. Adult Wistar …

Melatonin in edible plants (phytomelatonin): identification, concentrations, bioavailability and proposed functions

RJ Reiter, D Tan, LC Manchester… - More on Mediterranean …, 2007 - karger.com
The discovery of melatonin (N-acetyl-5-methoxytryptamine) in plants occurred just over a
decade ago [1–3]. For roughly 35 years before that, melatonin was known to be the indole …

Melatonin: new places in therapy

DS Maharaj, BD Glass, S Daya - Bioscience reports, 2007 - portlandpress.com
The fact that the full extent of the function of the pineal gland has not yet been elucidated,
has stimulated melatonin research worldwide. This review introduces melatonin's …