[PDF][PDF] Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans.

R Reiter, D Tan, J Mayo, R Sainz, J Leon… - Acta Biochimica …, 2003 - bibliotekanauki.pl
This brief resume enumerates the multiple actions of melatonin as an antioxidant. This
indoleamine is produced in the vertebrate pineal gland, the retina and possibly some other …

[HTML][HTML] Melatonin possesses an anti-influenza potential through its immune modulatory effect

SH Huang, CL Liao, SJ Chen, LG Shi, L Lin… - Journal of Functional …, 2019 - Elsevier
Influenza is an infectious disease caused by an RNA virus that affects birds and mammals. It
is a leading cause of morbidity, mortality and economic loss worldwide. Under influenza A …

Evaluating the oxidative stress in inflammation: role of melatonin

A Sánchez, AC Calpena, B Clares - International journal of molecular …, 2015 - mdpi.com
Oxygen is used by eukaryotic cells for metabolic transformations and energy production in
mitochondria. Under physiological conditions, there is a constant endogenous production of …

Melatonin reverses lipopolysaccharide‐induced gastro‐intestinal motility disturbances through the inhibition of oxidative stress

D De Filippis, T Iuvone, G Esposito… - Journal of pineal …, 2008 - Wiley Online Library
A growing number of reports demonstrate that a pro‐inflammatory and oxidative condition is
related to the pathogenesis and the progression of endotoxin‐induced septic shock and that …

Melatonin as an antioxidant and immunomodulator in atopic dermatitis—A new look on an old story: A Review

AK Jaworek, JC Szepietowski, P Hałubiec… - Antioxidants, 2021 - mdpi.com
Atopic dermatitis (AD) is common inflammatory dermatosis, typically with chronic and
recurrent course, which significantly reduces the quality of life. Sleep disturbances are …

Melatonin in relation to physiology in adult humans: Mini Review

A Cagnacci - Journal of pineal research, 1996 - Wiley Online Library
The role exerted by melatonin in human physiology has not been completely ascertained.
Melatonin levels have been measured in different physiopathological conditions, but the …

[HTML][HTML] Natural ingredients to improve immunity

A Gasmi, M Shanaida, O Oleshchuk, Y Semenova… - Pharmaceuticals, 2023 - mdpi.com
The immune system protects the body from infectious agents such as bacteria, viruses, or
fungi. Once encountered with pathogens or antigens, the innate and adaptive arms of the …

Effect of melatonin supplementation on oxidative stress parameters: a systematic review and meta-analysis

M Morvaridzadeh, E Sadeghi, S Agah… - Pharmacological …, 2020 - Elsevier
Background Oxidative stress, defined as an imbalance between pro-oxidants and
neutralizing antioxidants within the body, is a growing public health concern. Oxidative …

Melatonin: Protection against age-related cardiac pathology

G Favero, L Franceschetti, B Buffoli… - Ageing research …, 2017 - Elsevier
Aging is a complex and progressive process that involves physiological and metabolic
deterioration in every organ and system. Cardiovascular diseases are one of the most …

[HTML][HTML] Melatonin: exceeding expectations

RJ Reiter, DX Tan, A Galano - Physiology, 2014 - journals.physiology.org
Melatonin is a small, highly conserved indole with numerous receptor-mediated and
receptor-independent actions. Receptor-dependent functions include circadian rhythm …