The perception of pain is altered by inflammatory processes. Anti‐inflammatory drugs block
this by raising the pain threshold and by reducing the inflammatory process. Melatonin is …

Human life expectancy has increased over the past 50 years due to scientific and medical
advances and higher food availability. However, overweight and obesity affect more than …

During the last 20 years, numerous clinical trials have examined the therapeutic usefulness
of melatonin in different fields of medicine. The objective of this article is to review, in depth …

The functional versatility and diversity of melatonin has exceeded everyone's expectations.
The evidence is substantial that melatonin has multiple receptor-mediated and receptor …

The antiulcer effect of melatonin on gastric lesions caused by restraint‐cold stress was
studied with the intent of determining the mechanism of action of this agent. Melatonin dose …

Melatonin (N-acetyl-5-methoxytryptamine) is a nontoxic biological molecule produced in a
pineal gland of animals and different tissues of plants. It is an important secondary …

A vast number of experimental and clinical studies implicates oxygen-derived free radicals
(especially, superoxide and the hydroxyl radical) and high energy oxidants (such as …

Inflammation and oxidative process are associated with inflammatory bowel disease (IBD).
Regarding anti-inflammatory and antioxidant potentials, melatonin has been found …

After being discovered from the bovine pineal gland by Aaron Lerner and co-workers in the
year 1958, various distinguished researchers have reported melatonin (5-methoxy-N-acetyl …

Highlights•The contributing factors on melatonin amounts in different fruits are
reviewed.•The current analytical approaches of melatonin in fruits are discussed.•The …