Protective effect of melatonin in carrageenan‐induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite …

S Cuzzocrea, B Zingarelli, E Gilad… - Journal of pineal …, 1997 - Wiley Online Library
Cuzzocrea S, Zingarelli B, Gilad E, Hake P, Salzman AL, Szabó C. Protective effect of
melatonin in carrageenan‐induced models of local inflammation: Relationship to its …

Melatonin natural health products and supplements: presence of serotonin and significant variability of melatonin content

LAE Erland, PK Saxena - Journal of Clinical Sleep Medicine, 2017 - jcsm.aasm.org
Study Objectives: Melatonin is an important neurohormone, which mediates circadian
rhythms and the sleep cycle. As such, it is a popular and readily available supplement for the …

Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger

DX Tan, RJ Reiter, LC Manchester… - Current topics in …, 2002 - ingentaconnect.com
Melatonin was found to be a potent free radical scavenger in 1993. Since then over 800
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …

The immunotherapeutic potential of melatonin

GJM Maestroni - Expert opinion on investigational drugs, 2001 - Taylor & Francis
The interaction between the brain and the immune system is essential for the adaptive
response of an organism against environmental challenges. In this context, the pineal …

Reactive oxygen species-induced gastric ulceration: protection by melatonin

D Bandyopadhyay… - Current Medicinal …, 2006 - ingentaconnect.com
Gastric hyperacidity and ulceration of the stomach mucosa due to various factors are serious
health problems of global concern. Although the mechanism of acid secretion from the …

The neuroprotective effects of melatonin: Possible role in the pathophysiology of neuropsychiatric disease

JG Lee, YS Woo, SW Park, DH Seog, MK Seo… - Brain sciences, 2019 - mdpi.com
Melatonin is a hormone that is secreted by the pineal gland. To date, melatonin is known to
regulate the sleep cycle by controlling the circadian rhythm. However, recent advances in …

Melatonin in Chinese medicinal herbs

G Chen, Y Huo, DX Tan, Z Liang, W Zhang, Y Zhang - Life sciences, 2003 - Elsevier
Melatonin is a highly conserved molecule that not only exists in animals, but also is present
in bacteria, unicellular organisms and in plants. Since melatonin is an antioxidant, in plants …

New perspectives in melatonin uses

A Carpentieri, GD De Barboza, V Areco… - Pharmacological …, 2012 - Elsevier
This review summarizes the metabolism, secretion, regulation and sites of action of
melatonin. An updated description of the melatonin receptors, including their signal …

Melatonin and nitric oxide

S Aydogan, MB Yerer, A Goktas - Journal of endocrinological investigation, 2006 - Springer
Melatonin is a product of the amino acid tryptophan in the pineal gland. Once synthesized,
the specific mechanisms governing the release of melatonin from the pineal gland and its …

Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography‐mass spectrometry

R Dubbels, RJ Reiter, E Klenke… - Journal of pineal …, 1995 - Wiley Online Library
Melatonin, the chief hormone of the pineal gland in vertebrates, is widely distributed in the
animal kingdom. Among many functions, melatonin synchronizes circadian and circannual …