Melatonin redox activity. Its potential clinical applications in neurodegenerative disorders

E Miller, A Morel, L Saso, J Saluk - Current topics in medicinal …, 2015 - ingentaconnect.com
Neurodegeneration is the hallmark of many chronic progressive neurogical disorders
characterized by specific clinical, morphological and biochemical features. Central nervous …

Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action

PP Posadzki, R Bajpai, BM Kyaw, NJ Roberts… - BMC medicine, 2018 - Springer
Background Our aims were to evaluate critically the evidence from systematic reviews as
well as narrative reviews of the effects of melatonin (MLT) on health and to identify the …

Growth conditions influence the melatonin content of tomato plants

MB Arnao, J Hernández-Ruiz - Food chemistry, 2013 - Elsevier
Melatonin (N-acetyl-5-methoxytryptamine) is an interesting molecule with well-known
functions in vertebrates. Since its discovery in plants in 1995, many data indicate that its role …

Melatonin and health: insights of melatonin action, biological functions, and associated disorders

SB Ahmad, A Ali, M Bilal, SM Rashid, AB Wani… - Cellular and Molecular …, 2023 - Springer
Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

Melatonin as an antioxidant: under promises but over delivers

RJ Reiter, JC Mayo, DX Tan, RM Sainz… - Journal of pineal …, 2016 - Wiley Online Library
Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …

Melatonin in macrophage biology: Current understanding and future perspectives

Y Xia, S Chen, S Zeng, Y Zhao, C Zhu… - Journal of pineal …, 2019 - Wiley Online Library
Melatonin is a ubiquitous hormone found in various organisms and highly affects the
function of immune cells. In this review, we summarize the current understanding of the …

Protective effect of melatonin in a non‐septic shock model induced by zymosan in the rat

S Cuzzocrea, B Zingarelli, G Costantino… - Journal of pineal …, 1998 - Wiley Online Library
In vitro studies have demonstrated that melatonin is a scavenger of oxyradicals and
peroxynitrite and an inhibitor of nitric oxide (NO) production. Recently, it has been proposed …

Melatonin: pharmacology, functions and therapeutic benefits

S Tordjman, S Chokron, R Delorme… - Current …, 2017 - ingentaconnect.com
Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal
gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of …

Melatonin: an antioxidant in edible plants

RJ Reiter, DUNX TAN - Annals of the New York Academy of …, 2002 - Wiley Online Library
Melatonin, a molecule with antioxidant properties that is widely distributed in the animal
kingdom, has now been shown to exist in the plant kingdom, including edible plants. Our …

A systematic review of melatonin in plants: an example of evolution of literature

SJ Murch, LAE Erland - Frontiers in Plant Science, 2021 - frontiersin.org
Melatonin (N-acetyl-5-methoxy-tryptamine) is a mammalian neurohormone, antioxidant and
signaling molecule that was first discovered in plants in 1995. The first studies investigated …