Melatonin as a potential approach to anxiety treatment

K Repova, T Baka, K Krajcirovicova, P Stanko… - International journal of …, 2022 - mdpi.com
Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

Effects of melatonin on cardiovascular risk factors and metabolic syndrome: a comprehensive review

M Imenshahidi, G Karimi, H Hosseinzadeh - … -Schmiedeberg's Archives of …, 2020 - Springer
Melatonin, as a neuroendocrine hormone, is produced primarily by the pineal gland.
Melatonin, a pleotropic molecule, acts as a free radical scavenger, antioxidant, and regulator …

Melatonin: Genel özellikleri ve psikiyatrik bozukluklardaki rolü

F Özçelik, M Erdem, A Bolu, M Gülsün - Psikiyatride Güncel …, 2013 - dergipark.org.tr
In recent years, there is a growing interest in melatonin all over the world. The main task of
protecting the body's biological clock, which set the rhythm of melatonin, involves many …

Evidence of melatonin synthesis and release by mast cells. Possible modulatory role on inflammation

MD Maldonado, M Mora-Santos, L Naji… - Pharmacological …, 2010 - Elsevier
Mast cells take part of armamentarium immunologic for host defense against parasitic and
bacterial infections. They are derived from bone marrow progenitors and can be activated by …

Effects of exogenous melatonin—a review

VN Anisimov - Toxicologic pathology, 2003 - journals.sagepub.com
The results of studies on the effect of pineal indole hormone melatonin on the life span of
mice, rats, fruit flies, and worms are critically reviewed. In mice, long-term administration of …

Adverse events associated with oral administration of melatonin: A critical systematic review of clinical evidence

HM Foley, AE Steel - Complementary therapies in medicine, 2019 - Elsevier
While melatonin was once thought of simply as a sleep-inducing hormone, recent research
has resulted in development of a deeper understanding of the complex physiological activity …

Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases

GJ Lin, SH Huang, SJ Chen, CH Wang… - International journal of …, 2013 - mdpi.com
Melatonin is the major secretory product of the pineal gland during the night and has
multiple activities including the regulation of circadian and seasonal rhythms, and …

Melatonin, aging, and age-related diseases: perspectives for prevention, intervention, and therapy

B Poeggeler - Endocrine, 2005 - Springer
The high incidence of age-related diseases in the increasing population of elderly people
has stimulated interest in the search for protective agents that have the capability of …

Melatonin and phytomelatonin: Chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animals—An overview

G Mannino, C Pernici, G Serio, C Gentile… - International Journal of …, 2021 - mdpi.com
Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of
several physiological processes in both animals and plants. In the last century, it was …

Melatonin from microorganisms, algae, and plants as possible alternatives to synthetic melatonin

MB Arnao, M Giraldo-Acosta, A Castejón-Castillejo… - Metabolites, 2023 - mdpi.com
Melatonin dietary supplements are widely consumed worldwide, with developed countries
as the largest consumers, with an estimated annual growth rate of approximately 10% until …