The presence of the peptide substance P in small unmyelinated primary sensory neurons 5
appears to be related to the transmission of nociceptive impulses at the level of the spinal …

The peptide substance P is highly concentrated in terminals of small diameter primary
sensory neurones located within the substantia gelatinosa of the dorsal horn of the spinal …

Substance P is contained within a subpopulation of nociceptive primary sensory neurons
that project to the superficial dorsal horn of the spinal cord. Stimulation of the peripheral …

A group of small-diameter primary afferent neurons synthesize substance P and transport
the peptide to their central and peripheral nerve endings, where it is released when the …

The in vitro release of immunoreactive substance P (I-SP) by capsaicin and three congeners
was studied on slices of rat spinal cord upper dorsal horn. Capsaicin and its congeners were …

Substance P (SP) is present in unmyelinated primary afferent fibres entering the spinal cord
(Hokfelt et al 1975) and has been suggested to be involved in pain transmission in the …

Substance P (SP) injected into intraspinal (is) spaces caused mice to vigorously scratch and
bite their skins in an apparent reaction to a perceived cutaneous sensation. The scratching …

Capsaicin has been shown to evoke the release of substance P (SP) from small diameter
primary afferent fibers. Using an in vivo perfusion of the rat spinal cord, this study examined …

The release of substance P (SP) from slices of hypothalamus, substantia nigra and spinal
cord of the rat was studied. In contrast to 47 mM potassium, capsaicin induced SP release …

Capsaicin, 8-methyl-N-vanillyl-6-nonenamide, is the pungent algesic substance of the red
pepper. On local or systemic injection capsaicin causes a marked stimulation of peripheral …