The gut microbiota has a great impact on the host immune systems. Recent evidence
suggests that the maternal gut microbiota affects the immune systems of offspring …

Mechanisms underlying modern increases in prevalence of human inflammatory diseases
remain unclear. The hygiene hypothesis postulates that decreased microbial exposure has …

Diets rich in saturated fats have become a staple globally. Fifty percent of women of
childbearing age in the United States are obese or overweight, with diet being a significant …

Background: Accumulating evidence shows that high fat diet is closely associated with
inflammatory bowel disease. However, the effects and underlying mechanisms of maternal …

Scope The transgenerational impact of dietary fat remains unclear. Here, the role of
maternal fat consumption as a modulator of gut microbial communities and infectious …

Food contains several components that are essential for health. Dietary fibres are
nondigestible foods that play an important role in the maintenance of health. Nondigestible …

Short-chain fatty acids (SCFAs), the end products of dietary fiber, influence the immune
system. Moreover, during pregnancy the maternal microbiome has a great impact on the …

We recently hypothesized that the intestinal microbiota and the innate immune system play
key roles in the mechanism of Kilham Rat Virus-induced type 1 diabetes in the LEW1. WR1 …

The gut and genital tract microbiota of females represent very complex biological
ecosystems that are in continuous communication with each other. The crosstalk between …

Immune tolerance deletes or suppresses autoreactive lymphocytes and is established at
multiple levels during the development, activation and effector phases of T and B cells …