[HTML][HTML] Risk of gallstones based on ABCG8 rs11887534 single nucleotide polymorphism among Taiwanese men and women
Background Gallstones are abnormal masses caused by impaired metabolism of
cholesterol, bilirubin, or bile salts in the gallbladder or biliary tract. ATP-binding cassette …
cholesterol, bilirubin, or bile salts in the gallbladder or biliary tract. ATP-binding cassette …
Role of ABCG8 D19H (rs11887534) variant in gallstone susceptibility in northern India
Abstract Background and Aim: The excretion of cholesterol from the liver is regulated by the
ATP‐binding cassette transporter ABCG8. A common genetic polymorphism D19H of …
ATP‐binding cassette transporter ABCG8. A common genetic polymorphism D19H of …
Significant association of ABCG5 604Q and ABCG8 D19H polymorphisms with gallstone disease
KK Kuo, SJ Shin, ZC Chen, YHC Yang… - Journal of British …, 2008 - academic.oup.com
Background Adenosine triphosphate-binding cassette (ABC) transporters ABCG5 and
ABCG8 are sterol export pumps regulating biliary cholesterol excretion. The formation of …
ABCG8 are sterol export pumps regulating biliary cholesterol excretion. The formation of …
[HTML][HTML] Correlation of serum biochemical characteristics and ABCG8 genetic variant (rs 11887534) with gall stone compositions and risk of gallstone disease in …
DM Aly, AM Fteah, NM Al Assaly, MA Elashry… - Asian Journal of …, 2023 - Elsevier
Background The overexpression of the cholesterol transporter: ATP-binding cassette
transporter (ABCG8) due to the effect of ABCG8 genetic variant (rs11887534) leads to the …
transporter (ABCG8) due to the effect of ABCG8 genetic variant (rs11887534) leads to the …
[HTML][HTML] Prevalence of ABCB4 polymorphisms in gallstone disease in han-Chinese population
L Zhan, YZ Pan, L Chen, H Zhang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Abstract ATP Binding Cassette Transporter A4 (ABCB4) is a sterol export pump that
regulates excretion of biliary cholesterol. We tested association between ABCB4 …
regulates excretion of biliary cholesterol. We tested association between ABCB4 …
Four susceptibility loci for gallstone disease identified in a meta-analysis of genome-wide association studies
Background & Aims A genome-wide association study (GWAS) of 280 cases identified the
hepatic cholesterol transporter ABCG8 as a locus associated with risk for gallstone disease …
hepatic cholesterol transporter ABCG8 as a locus associated with risk for gallstone disease …
[HTML][HTML] Association of three common single nucleotide polymorphisms of ATP binding cassette G8 gene with gallstone disease: a meta-analysis
ZY Jiang, Q Cai, EZ Chen - PloS one, 2014 - journals.plos.org
Background In this study, we evaluated the association between these polymorphisms and
gallstone disease using meta-analysis and compared the hepatic ABCG5/G8 mRNA …
gallstone disease using meta-analysis and compared the hepatic ABCG5/G8 mRNA …
The ABCG8 polymorphism increases the risk of gallbladder cancer in the general population and gallstones in obese patients from Poland
L Krupa, P Kalinowski, J Ligocka… - European Journal of …, 2024 - Wiley Online Library
Background Gallstone disease (GD) is common but remains asymptomatic in most cases.
However, gallstones can lead to complications like choledocholithiasis or gallbladder …
However, gallstones can lead to complications like choledocholithiasis or gallbladder …
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease
With an overall prevalence of 10–20%, gallstone disease (cholelithiasis) represents one of
the most frequent and economically relevant health problems of industrialized countries,. We …
the most frequent and economically relevant health problems of industrialized countries,. We …
Hepatic cholesterol transporter ABCG8 polymorphisms in gallstone disease in an Indian population
SP Siddapuram, S Mahurkar… - Journal of …, 2010 - Wiley Online Library
Abstract Background and Aim: Gallstone formation is characterized by the abnormal
regulation of cholesterol trafficking and solubilization. The prevalence of gallstone disease …
regulation of cholesterol trafficking and solubilization. The prevalence of gallstone disease …