Most of the iron in a mammalian body is complexed with various proteins. Moreover, in
response to infection, iron availability is reduced in both extracellular and intracellular …

The proliferative capability of many invasive pathogens is limited by the bioavailability of
iron. Pathogens have thus developed strategies to obtain iron from their host organisms. In …

In the human body iron is present in growth-limiting amounts for bacteria. For this reason
intricate iron transport and iron regulatory systems evolved in bacteria to guarantee a …

The ability of microorganisms that would like to live in or on mammalian hosts to acquire iron
is a critical determinant of the host-parasite interaction. Despite the abundance of iron, its …

Bacteria that reside in animal tissues and/or cells must acquire iron from their host. However,
almost all of the host iron is sequestered in iron-containing compounds and proteins, the …

Siderophores are biosynthetically produced and secreted by many bacteria, yeasts, fungi
and plants, to scavenge for ferric iron (Fe 3+). They are selective iron-chelators that have an …

Preface. Iron is considered to be a minor element employed, in a variety of forms, by nearly
all living organisms. In some cases, it is utilised in large quantities, for instance for the …

For the majority of bacterial pathogens, acquisition of iron from host proteins is a prerequisite
for growth during infection. The mechanisms by which Gram-negative bacteria obtain iron …

BACKGROUND: To successfully sustain an infection, nearly all bacteria, fungi and protozoa
require a continuous supply of host iron. METHODS: Literature review. RESULTS …

Iron is now recognized as playing a vital role in infection. Not only does its restricted
availability in tissue fluids present microbial pathogens with the problem of acquiring …