[HTML][HTML] Cryptotanshinone protects hippocampal neurons against oxygen-glucose deprivation-induced injury through the activation of Nrf2/HO-1 signaling pathway

D Xu, C Gui, H Zhao, F Liu - Food Science and Technology, 2021 - SciELO Brasil
Cryptotanshinone (CPT), a terpenoid isolated from the roots of Salvia miltiorrhiza Bunge,
was reported to have neuroprotective effects against cerebral ischemic stroke. However, the …

Cryptotanshinone Attenuates Oxygen-Glucose Deprivation/ Recovery-Induced Injury in an in vitro Model of Neurovascular Unit

H Zhao, T Zheng, X Yang, M Fan, L Zhu, S Liu… - Frontiers in …, 2019 - frontiersin.org
Cryptotanshinone (CTs), an active component isolated from the root of Salvia miltiorrhiza
(SM), has been shown to exert potent neuroprotective property. We here established an …

Neuroprotective effect of swertiamain on cerebral ischemia/reperfusion injury by inducing the Nrf2 protective pathway

H Wang, W Wei, X Lan, N Liu, Y Li, H Ma… - ACS chemical …, 2019 - ACS Publications
Oxidative stress plays a vital role in the development of cerebral ischemic/reperfusion (I/R).
Targeting oxidative stress is proposed to be an effective strategy to treat cerebral I/R injury …

Taraxasterol protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activation of Nrf2 signalling pathway

Y He, K Jiang, X Zhao - Artificial Cells, Nanomedicine, and …, 2020 - Taylor & Francis
Cerebral ischemia/reperfusion (I/R) injury is a brain injury following ischaemic stroke that is
associated with oxidative stress. Taraxasterol, a natural product, has been shown to have …

Neuroprotection of Cyperus esculentus L. orientin against cerebral ischemia/reperfusion induced brain injury

SQ Jing, SS Wang, RM Zhong, JY Zhang… - Neural regeneration …, 2020 - journals.lww.com
Orientin is a flavonoid monomer. In recent years, its importance as a source of
pharmacological active substance is growing rapidly due to its properties such as anti …

Neohesperidin attenuates cerebral ischemia–reperfusion injury via inhibiting the apoptotic pathway and activating the Akt/Nrf2/HO-1 pathway

JJ Wang, P Cui - Journal of Asian natural products research, 2013 - Taylor & Francis
Oxidative stress is well known to play a pivotal role in cerebral ischemia–reperfusion injury.
On the basis of this fact, antioxidative agents have been demonstrated to be neuroprotective …

Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK …

M Sugimoto, R Ko, H Goshima, A Koike, M Shibano… - Neurotoxicology, 2021 - Elsevier
Formononetin is an isoflavone, found in herbs like Trifolium pratense, which executes a
variety of physiological activities including anti-neurodegenerative effect. However, the …

Astilbin exerts a neuroprotective effect by upregulating the signaling of nuclear NF-E2-related factor 2 in vitro

C Guo, Y Yin, Z Ma, F Xu, S Wang - Heliyon, 2024 - cell.com
Objective The present study aims to evaluate the impact of Astilbin (AST) on cortical neuron
survival in vitro under conditions of oxygen-glucose deprivation and reoxygenation (OGD/R) …

The Phenolic Components of Gastrodia elata improve Prognosis in Rats after Cerebral Ischemia/Reperfusion by Enhancing the Endogenous Antioxidant …

A Shi, J Xiang, F He, Y Zhu, G Zhu… - … Medicine and Cellular …, 2018 - Wiley Online Library
Pharmacological or spontaneous thrombolysis in ischemic stroke triggers an outbreak of
reactive oxygen species and results in neuron death. Nrf2‐mediated antioxidation in cells …

Magnoflorine Attenuates Cerebral Ischemia‐Induced Neuronal Injury via Autophagy/Sirt1/AMPK Signaling Pathway

H Liang, X Chang, R Xia, W Wu… - Evidence‐Based …, 2022 - Wiley Online Library
Ischemic stroke is a common cause of permanent disability worldwide. Magnoflorine has
been discovered to have good antioxidation, immune regulation, and cardiovascular system …