Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans

RD Brook, B Urch, JT Dvonch, RL Bard, M Speck… - …, 2009 - Am Heart Assoc
Fine particulate matter air pollution plus ozone impairs vascular function and raises diastolic
blood pressure. We aimed to determine the mechanism and air pollutant responsible. The …

Particulate matter, air pollution, and blood pressure

RD Brook, S Rajagopalan - Journal of the American Society of …, 2009 - Elsevier
A short-term increase in fine particulate matter air pollution (PM2. 5) concentration increases
the risk for myocardial infarctions, strokes, and heart failure exacerbations. An important …

Acute blood pressure responses in healthy adults during controlled air pollution exposures

B Urch, F Silverman, P Corey, JR Brook… - Environmental …, 2005 - ehp.niehs.nih.gov
Exposure to air pollution has been shown to cause arterial vasoconstriction and alter
autonomic balance. Because these biologic responses may influence systemic …

Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults

RD Brook, JR Brook, B Urch, R Vincent… - Circulation, 2002 - Am Heart Assoc
Background—Fine particulate air pollution and ozone are associated with increased
cardiovascular events. To help explain the mechanism behind these observations, we …

Air pollution: the" Heart" of the problem

RD Brook, JR Brook, S Rajagopalan - Current hypertension reports, 2003 - Springer
Air pollution exposure is associated with an increased risk of acute and chronic
cardiovascular mortality. Recent observations have implicated fine particulate matter (PM …

Effects of gaseous and solid constituents of air pollution on endothelial function

T Münzel, T Gori, S Al-Kindi, J Deanfield… - European heart …, 2018 - academic.oup.com
Ambient air pollution is a leading cause of non-communicable disease globally. The largest
proportion of deaths and morbidity due to air pollution is now known to be due to …

Exposure to airborne fine particulate matter is associated with impaired endothelial function and biomarkers of oxidative stress and inflammation

DW Riggs, N Zafar, S Krishnasamy, R Yeager… - Environmental …, 2020 - Elsevier
Epidemiological evidence suggests that exposure to air pollution is a leading risk factor for
cardiovascular disease (CVD). However, there is little direct evidence linking exposure to …

Air pollution exposure and blood pressure: an updated review of the literature

P Giorgini, P Di Giosia, D Grassi… - Current …, 2016 - ingentaconnect.com
Both high arterial blood pressure (BP) and elevated levels of fine particulate matter (PM2. 5)
air pollution have been associated with an increased risk for several cardiovascular (CV) …

Effects of indoor, outdoor, and personal exposure to particulate air pollution on cardiovascular physiology and systemic mediators in seniors

L Liu, T Ruddy, M Dalipaj, R Poon… - … of Occupational and …, 2009 - journals.lww.com
Objective: To investigate the associations between exposure to particulate air pollution and
changes in cardiovascular function and plasma mediators in seniors. Methods: We …

Mechanisms of inhaled fine particulate air pollution–induced arterial blood pressure changes

CR Bartoli, GA Wellenius, EA Diaz… - Environmental …, 2009 - ehp.niehs.nih.gov
Background Epidemiologic studies suggest a positive association between fine particulate
matter and arterial blood pressure, but the results have been inconsistent. Objectives We …