Vasoprotection by nitric oxide: mechanisms and therapeutic potential

MT Gewaltig, G Kojda - Cardiovascular research, 2002 - academic.oup.com
Endothelial production of nitric oxide (nitrogen monoxide, NO) has become a major research
area in vascular biology. Some of the most important effects that NO exerts in the vascular …

[HTML][HTML] Endothelial nitric oxide synthase (eNOS) and the cardiovascular system: in physiology and in disease states

N Tran, T Garcia, M Aniqa, S Ali, A Ally… - American journal of …, 2022 - ncbi.nlm.nih.gov
Endothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining a
healthy cardiovascular system. The importance of eNOS can be emphasized from the …

[PDF][PDF] Nitric oxide signalling in the regulation of cardiovascular and platelet function

E Gkaliagkousi, A Ferro - Front Biosci, 2011 - academia.edu
Nitric oxide (NO) exerts important protective actions on the cardiovascular system.
Generated from L-arginine by the action of endothelial (or type 3) nitric oxide synthase …

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases

C Napoli, LJ Ignarro - Archives of pharmacal research, 2009 - Springer
Nitric oxide (NO) is a pivotal signaling messenger in the cardiovascular system. NO
participates in regulatory functions including control of hemostasis, fibrinolysis, platelet and …

[引用][C] Nitric oxide biology: implications for cardiovascular therapeutics

JB Warren, F Pons, AJB Brady - Cardiovascular research, 1994 - academic.oup.com
N elucidated the function of nitric oxide as a cardiovascular autacoid, since it was disovered
to be an endothelium derived relaxing fact0r. Ij It is now possible to foresee the potential of …

Nitric oxide—biological mediator, modulator and factor of injury: its role in the pathogenesis of atherosclerosis

MW Radomski, E Salas - Atherosclerosis, 1995 - Elsevier
Nitric oxide (NO) is generated from l-arginine by the family of isoenzymes called NO
synthases (NOS). Gene cloning has identified neuronal, endothelial and cytokine-inducible …

Cardiovascular diseases and the nitric oxide pathway

S Llorens, E Nava - Current vascular pharmacology, 2003 - ingentaconnect.com
Fifteen years after its discovery, NO has fully reached an established position in physiology,
medicine and therapeutics. It is difficult to find a biological function or a pathological …

Nitric oxide and coronary vascular endothelium adaptations in hypertension

AS Levy, JCS Chung, JT Kroetsch… - Vascular Health and …, 2009 - Taylor & Francis
This review highlights a number of nitric oxide (NO)-related mechanisms that contribute to
coronary vascular function and that are likely affected by hypertension and thus become …

Mechanisms of dysfunction of the nitric oxide pathway in vascular diseases

AJ Maxwell - Nitric oxide, 2002 - Elsevier
Vascular nitric oxide (NO) is involved in many physiologic and pathophysiologic processes
throughout the body. Many vascular diseases have a reduction in the activity of endothelium …

Expression and regulation of endothelial nitric oxide synthase

K Sase, T Michel - Trends in cardiovascular medicine, 1997 - Elsevier
Endothelium-derived nitric oxide (NO) is a key determinant of blood pressure homeostasis
and platelet aggregation and is synthesized by the endothelial isoform of nitric oxide …