Extensive bone defect repair remains a clinical challenge, since ideal implantable scaffolds
require the integration of excellent biocompatibility, sufficient mechanical strength and high …

Conventional biomaterials developed for bone regeneration fail to fully recapitulate the
nanoscale structural organization and complex composition of the native bone …

Periodontitis-induced alveolar bone defects necessitate the use of bone grafts for optimal
therapeutic outcomes. Therefore, synthetic bone grafts exhibiting consistent properties …

The combination of bioactive hydroxyapatite (HAp) with biomimetic bone matrix biomaterials
as bone filling scaffolds is a promising strategy for bone regeneration, but the undesirable …

Bone tissue engineering holds great promise for the regeneration of damaged or severe
bone defects. However, several challenges hinder its translation into clinical practice. To …

Calcium phosphate cement scaffold (CPC) has been widely used as bone graft substitutes,
but undesirable osteoinductivity and slow degradability greatly hamper their clinic …

Effective bone tissue engineering can restore bone and skeletal functions that are impaired
by traumas and/or certain medical conditions. Bone is a complex tissue and functions …

In contrast to sintered calcium phosphates (CaPs) commonly employed as scaffolds to
deliver mesenchymal stromal cells (MSCs) targeting bone repair, low temperature setting …

Various therapeutic platforms have been developed for repairing bone defects. However,
scaffolds possess both cortical bone-matching mechanical properties and excellent …

Inspired by the nanostructure of bone, biomimetic nanocomposites comprising natural
polymers and inorganic nanoparticles have gained much attention for bone regenerative …