[PDF][PDF] Is chronic fatigue the symptom of venous insufficiency associated with multiple sclerosis? A longitudinal pilot study

AM Malagoni, R Galeotti, E Menegatti, F Manfredini… - Int Angiol, 2010 - researchgate.net
Aim. Chronic fatigue (CF) severely affects patients with mul-tiple sclerosis (MS), but its
pathogenesis remains elusive and the effectiveness of available treatments is modest. We …

Occurrence of CCSVI in patients with MS and its relationship with iron metabolism and varicose veins

PJ Van den Berg, GB Van den Berg… - European journal of …, 2013 - Wiley Online Library
Background and purpose A new treatable venous disorder, chronic cerebrospinal venous
insufficiency (CCSVI), has been proposed in patients with multiple sclerosis (MS). Its …

[HTML][HTML] Chronic cerebrospinal venous insufficiency is not associated with multiple sclerosis and its severity: a blind-verified study

MA Leone, O Raymkulova, P Naldi, P Lochner… - PLoS …, 2013 - journals.plos.org
Background Chronic Cerebrospinal Venous Insufficiency (CCSVI) has been associated with
multiple sclerosis (MS) with a risk ranging from as high as two-hundred-fold to a protective …

[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon

R Lanzillo, M Mancini, R Liuzzi, O Di Donato… - BMC neurology, 2013 - Springer
Background This study aimed to investigate the prevalence and clinical relevance of chronic
cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy …

[HTML][HTML] Dilatation of the bridging cerebral veins in multiple sclerosis correlates with fatigue and suggests an increase in pressure

GA Bateman, AR Bateman, J Lechner-Scott - Multiple Sclerosis and …, 2023 - Elsevier
Background There is a significant increase in the parenchymal microvessel blood volume in
the earliest forms of multiple sclerosis (MS) which may be due to venular dilatation …

[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: a historical perspective

MD Dake, R Zivadinov, EM Haacke - Functional neurology, 2011 - ncbi.nlm.nih.gov
Chronic cerebrospinal venous insufficiency (CCSVI) is a term used to describe impaired
venous drainage from the central nervous system (CNS) caused by abnormalities in …

[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study

S Bastianello, A Romani, G Viselner, EC Tibaldi… - BMC neurology, 2011 - Springer
Background Chronic cerebrospinal venous insufficiency (CCSVI) has recently been reported
to be associated with multiple sclerosis (MS). However, its actual prevalence, possible …

Brain hemodynamic changes associated with chronic cerebrospinal venous insufficiency are not specific to multiple sclerosis and do not increase its severity

FG Garaci, S Marziali, A Meschini, M Fornari, S Rossi… - Radiology, 2012 - pubs.rsna.org
Purpose To investigate the relationship between chronic cerebrospinal venous insufficiency
(CCSVI) and cerebral hemodynamic parameters and to disclose any possible involvement …

[HTML][HTML] Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study

IW Rodger, D Dilar, J Dwyer, J Bienenstock, A Coret… - PLoS …, 2013 - journals.plos.org
Objective Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS.
Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous …

Progressive multiple sclerosis is not associated with chronic cerebrospinal venous insufficiency

C Baracchini, P Perini, F Causin, M Calabrese… - Neurology, 2011 - AAN Enterprises
Objective: Chronic cerebrospinal venous insufficiency (CCSVI) had been suggested to play
a major pathogenetic role in multiple sclerosis (MS), but recent data on early stages of MS …