Regulation of human cytochrome P4501A1 (hCYP1A1): a plausible target for chemoprevention?
R Santes-Palacios, D Ornelas-Ayala… - BioMed research …, 2016 - Wiley Online Library
Human cytochrome P450 1A1 (hCYP1A1) has been an object of study due to its role in
precarcinogen metabolism; for this reason it is relevant to know more in depth the …
precarcinogen metabolism; for this reason it is relevant to know more in depth the …
Modulation of CYP1A1 metabolism: From adverse health effects to chemoprevention and therapeutic options
M Mescher, T Haarmann-Stemmann - Pharmacology & therapeutics, 2018 - Elsevier
The human cytochrome P450 (CYP) 1A1 gene encodes a monooxygenase that metabolizes
multiple exogenous and endogenous substrates. CYP1A1 has become infamous for its …
multiple exogenous and endogenous substrates. CYP1A1 has become infamous for its …
Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention
CYP1A1 is one of the main cytochrome P450 enzymes, examined extensively for its capacity
to activate compounds with carcinogenic properties. Continuous exposure to inhalation …
to activate compounds with carcinogenic properties. Continuous exposure to inhalation …
The role of CYP3A in health and disease
LS Klyushova, ML Perepechaeva, AY Grishanova - Biomedicines, 2022 - mdpi.com
CYP3A is an enzyme subfamily in the cytochrome P450 (CYP) superfamily and includes
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …
Role of the modulation of CYP1A1 expression and activity in chemoprevention
As one of the main extra‐hepatic cytochrome P450 (CYP) enzymes, CYP1A1 has been
comprehensively investigated for its ability to metabolize both exogenous and endogenous …
comprehensively investigated for its ability to metabolize both exogenous and endogenous …
Metabolism and mechanism of human cytochrome P450 enzyme 1A2
Human cytochrome P450 enzyme 1A2 (CYP1A2) is one of the most important cytochrome
P450 (CYP) enzymes in the liver, accounting for 13% to 15% of hepatic CYP enzymes …
P450 (CYP) enzymes in the liver, accounting for 13% to 15% of hepatic CYP enzymes …
Human cytochrome P4501A2.
MT Landi, R Sinha, NP Lang… - IARC scientific …, 1999 - europepmc.org
CYP1A2, a member of the cytochrome P450 superfamily (CYPs), is involved in the metabolic
activation of several carcinogens, among them aromatic and heterocyclic amines …
activation of several carcinogens, among them aromatic and heterocyclic amines …
Biological roles of cytochrome P450 1A1, 1A2, and 1B1 enzymes
YJ Kwon, S Shin, YJ Chun - Archives of pharmacal research, 2021 - Springer
Human cytochrome P450 enzymes (CYPs) play a critical role in various biological
processes and human diseases. CYP1 family members, including CYP1A1, CYP1A2, and …
processes and human diseases. CYP1 family members, including CYP1A1, CYP1A2, and …
Molecular role of cytochrome P4501A enzymes in oxidative stress
R Stading, C Chu, X Couroucli, K Lingappan… - Current opinion in …, 2020 - Elsevier
Summary Cytochrome P4501A (CYP1A) enzymes play important roles in xenobiotic and
endobiotic metabolism. Owing to uncoupling reactions during the enzymatic cycle, CYP1A …
endobiotic metabolism. Owing to uncoupling reactions during the enzymatic cycle, CYP1A …
[HTML][HTML] Expression of CYP2A3 mRNA and its regulation by 3-methylcholanthrene, pyrazole, and ß-ionone in rat tissues
AB Robottom-Ferreira, SR Aquino… - Brazilian journal of …, 2003 - SciELO Brasil
Cytochrome P450 (CYP) 2A enzymes are involved in the metabolism of numerous drugs
and hormones and activate different carcinogens. Human CYP2A6, mouse CYP2A5 and rat …
and hormones and activate different carcinogens. Human CYP2A6, mouse CYP2A5 and rat …