Mechanisms and context underlying the role of autophagy in cancer metastasis
Macroautophagy/autophagy is a fundamental cellular degradation mechanism that
maintains cell homeostasis, regulates cell signaling, and promotes cell survival. Its role in …
maintains cell homeostasis, regulates cell signaling, and promotes cell survival. Its role in …
Autophagy in cancer metastasis
EE Mowers, MN Sharifi, KF Macleod - Oncogene, 2017 - nature.com
Autophagy is a highly conserved self-degradative process that has a key role in cellular
stress responses and survival. Recent work has begun to explore the function of autophagy …
stress responses and survival. Recent work has begun to explore the function of autophagy …
The double-edged sword of autophagy modulation in cancer
E White, RS DiPaola - Clinical cancer research, 2009 - AACR
Macroautophagy (autophagy) is a lysosomal degradation pathway for the breakdown of
intracellular proteins and organelles. Although constitutive autophagy is a homeostatic …
intracellular proteins and organelles. Although constitutive autophagy is a homeostatic …
Autophagy: cancer's friend or foe?
The functional relevance of autophagy in tumor formation and progression remains
controversial. Autophagy can promote tumor suppression during cancer initiation and …
controversial. Autophagy can promote tumor suppression during cancer initiation and …
Functions of autophagy in the tumor microenvironment and cancer metastasis
EE Mowers, MN Sharifi, KF Macleod - The FEBS journal, 2018 - Wiley Online Library
Macro‐autophagy is an ancient and highly conserved self‐degradative process that plays a
homeostatic role in normal cells by eliminating organelles, pathogens, and protein …
homeostatic role in normal cells by eliminating organelles, pathogens, and protein …
The evolving, multifaceted roles of autophagy in cancer
J Liu, J Debnath - Advances in cancer research, 2016 - Elsevier
Autophagy is a lysosomal degradation process crucial for adaptation to stress and cellular
homeostasis. In cancer, autophagy has been demonstrated to serve multifaceted roles in …
homeostasis. In cancer, autophagy has been demonstrated to serve multifaceted roles in …
Autophagy as a therapeutic target in cancer
N Chen, V Karantza - Cancer biology & therapy, 2011 - Taylor & Francis
Autophagy is a self-catabolic process that maintains intracellular homeostasis and prolongs
cell survival under stress via lysosomal degradation of cytoplasmic constituents and …
cell survival under stress via lysosomal degradation of cytoplasmic constituents and …
Pro-survival autophagy: An emerging candidate of tumor progression through maintaining hallmarks of cancer
Autophagy is an evolutionary conserved catabolic process that regulates the cellular
homeostasis by targeting damaged cellular contents and organelles for lysosomal …
homeostasis by targeting damaged cellular contents and organelles for lysosomal …
Molecular mechanisms of autophagy in cancer development, progression, and therapy
VAM Vitto, S Bianchin, AA Zolondick, G Pellielo… - Biomedicines, 2022 - mdpi.com
Autophagy is an evolutionarily conserved and tightly regulated process that plays an
important role in maintaining cellular homeostasis. It involves regulation of various genes …
important role in maintaining cellular homeostasis. It involves regulation of various genes …
Molecular pathways: autophagy in cancer—a matter of timing and context
M Cicchini, V Karantza, B Xia - Clinical cancer research, 2015 - AACR
Autophagy is an intracellular self-digestion mechanism, by which cellular components are
sorted into double-membrane autophagosomes and delivered to lysosomes for degradation …
sorted into double-membrane autophagosomes and delivered to lysosomes for degradation …
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