[HTML][HTML] Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin
YS Ryu, KA Kang, MJ Piao, MJ Ahn, JM Yi, YM Hyun… - Redox biology, 2019 - Elsevier
Particulate matter (PM) increases levels of pro-inflammatory cytokines, but its effects on the
skin remain largely unknown. We investigated the signal transduction pathway and …
skin remain largely unknown. We investigated the signal transduction pathway and …
Transcriptome analysis of airborne PM2. 5-induced detrimental effects on human keratinocytes
HJ Kim, IH Bae, ED Son, J Park, N Cha, HW Na… - Toxicology letters, 2017 - Elsevier
Ambient air pollution is becoming more severe worldwide, posing a serious threat to human
health. Fine airborne particles of particulate matter (PM 2.5) show higher cytotoxicity than …
health. Fine airborne particles of particulate matter (PM 2.5) show higher cytotoxicity than …
Particulate matter induces pro‐inflammatory cytokines via phosphorylation of p38 MAPK possibly leading to dermal inflammaging
MJ Kim, JH Kim, GJ Jeong, KY Park… - Experimental …, 2019 - Wiley Online Library
Particulate matter (PM) is known to have harmful effects on human health. Epidemiological
studies have suggested that PM exposure is related to skin diseases and extrinsic skin …
studies have suggested that PM exposure is related to skin diseases and extrinsic skin …
[HTML][HTML] Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis
MJ Piao, MJ Ahn, KA Kang, YS Ryu, YJ Hyun… - Archives of …, 2018 - Springer
The skin is the largest organ of the human body and the one mostly exposed to outdoor
contaminants. To evaluate the biological mechanisms underlying skin damage caused by …
contaminants. To evaluate the biological mechanisms underlying skin damage caused by …
Urban particulate matter in air pollution penetrates into the barrier-disrupted skin and produces ROS-dependent cutaneous inflammatory response in vivo
SP Jin, Z Li, EK Choi, S Lee, YK Kim, EY Seo… - Journal of …, 2018 - Elsevier
Background Particulate matter (PM) is an integral part of air pollution, which is a mixture of
particles suspended in the air. Recently, it has been reported that PM is associated with …
particles suspended in the air. Recently, it has been reported that PM is associated with …
PM2. 5 exposure elicits oxidative stress responses and mitochondrial apoptosis pathway activation in HaCaT keratinocytes
R Hu, XY Xie, SK Xu, YN Wang, M Jiang… - Chinese medical …, 2017 - journals.lww.com
Background: PM 2.5 (aerodynamic diameter≤ 2.5 μm) is a dominant and ubiquitous air
pollutant that has become a global concern as PM 2.5 exposure has been linked to many …
pollutant that has become a global concern as PM 2.5 exposure has been linked to many …
[HTML][HTML] Particulate matter causes skin barrier dysfunction
BE Kim, J Kim, E Goleva, E Berdyshev, J Lee… - JCI insight, 2021 - ncbi.nlm.nih.gov
The molecular mechanisms that underlie the detrimental effects of particulate matter (PM) on
skin barrier function are poorly understood. In this study, the effects of PM 2.5 on filaggrin …
skin barrier function are poorly understood. In this study, the effects of PM 2.5 on filaggrin …
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β
Nanoparticles are increasingly used in various fields, including biomedicine and electronics.
One application utilizes the opacifying effect of nano-TiO2, which is frequently used as …
One application utilizes the opacifying effect of nano-TiO2, which is frequently used as …
[HTML][HTML] PM2. 5 induces apoptosis, oxidative stress injury and melanin metabolic disorder in human melanocytes
D Suo, S Zeng, J Zhang… - Experimental and …, 2020 - spandidos-publications.com
Recent growing evidence suggested that particulate matter 2.5 (PM2. 5) has strong toxic
effects on skin systems. However, the possible effects and the mechanisms of PM2. 5 on …
effects on skin systems. However, the possible effects and the mechanisms of PM2. 5 on …
Vitamin D3 ameliorates nitrogen mustard‐induced cutaneous inflammation by inactivating the NLRP3 inflammasome through the SIRT3–SOD2–mtROS signaling …
X Dong, Y He, F Ye, Y Zhao, J Cheng… - Clinical and …, 2021 - Wiley Online Library
Nitrogen mustard (NM) causes severe skin injury with an obvious inflammatory response,
which is lack of effective and targeted therapies. Vitamin D3 (VD3) has excellent anti …
which is lack of effective and targeted therapies. Vitamin D3 (VD3) has excellent anti …
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