The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity

JE Hollis-Moffatt, PJ Gow, AA Harrison… - Arthritis research & …, 2011 - Springer
Introduction The C allele of the nonsynonymous Arg265His (rs3733591) variant of SLC2A9
confers risk for gout in Han Chinese, Solomon Island and Japanese samples, with a …

Associations of a non-synonymous variant in SLC2A9 with gouty arthritis and uric acid levels in Han Chinese subjects and Solomon Islanders

HP Tu, CJ Chen, S Tovosia, AMS Ko, CH Lee… - Annals of the …, 2010 - ard.bmj.com
Objective To study the associations of gout, tophi and uric acid levels with the gout-related
SLC2A9 (solute carrier family 2, member 9) single nucleotide polymorphisms (SNPs) …

Associations between SLC2A9 polymorphisms and gout susceptibility: A meta-analysis.

YH Lee, YH Seo, JH Kim, SJ Choi, JD Ji… - Zeitschrift fur …, 2017 - europepmc.org
Objective The aim of this study was to determine whether polymorphisms in solute carrier
family 2 and facilitated glucose transporter member 9 (SLC2A9) are associated with …

Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study

YS Chang, CY Lin, TY Liu, CM Huang… - Arthritis Research & …, 2022 - Springer
Background Gout is a highly hereditary disease, but not all those carrying well-known risk
variants have developing gout attack even in hyperuricemia status. We performed a genome …

The SLC22A12 gene is associated with gout in Han Chinese and Solomon Islanders

HP Tu, CJ Chen, CH Lee, S Tovosia, AMS Ko… - Annals of the …, 2010 - ard.bmj.com
Gout is characterised by monosodium urate crystals in hyperuricaemic individuals. 1 2
Impaired excretion of urate exacerbates this condition. 1 Urate transporter 1 (encoded by …

Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case …

TJ Flynn, A Phipps-Green, JE Hollis-Moffatt… - Arthritis research & …, 2013 - Springer
Introduction There is inconsistent association between urate transporters SLC22A11
(organic anion transporter 4 (OAT4)) and SLC22A12 (urate transporter 1 (URAT1)) and risk …

Clinical significance of SLC2A9/GLUT9 rs11722228 polymorphisms in gout

E Das Gupta, R Sakthiswary, SL Lee… - International Journal …, 2018 - Wiley Online Library
Aim The main objective of this study is to elucidate the clinical significance of the SLC
2A9/GLUT 9 rs11722228 polymorphism among male gout patients. Method We …

Role of the urate transporter SLC2A9 gene in susceptibility to gout in New Zealand Māori, Pacific Island, and Caucasian case–control sample sets

JE Hollis‐Moffatt, X Xu, N Dalbeth… - … : Official Journal of …, 2009 - Wiley Online Library
Objective To examine the role of genetic variation in the renal urate transporter SLC2A9 in
gout in New Zealand sample sets of Māori, Pacific Island, and Caucasian ancestry and to …

Association between SLC2A9 (GLUT9) gene polymorphisms and gout susceptibility: an updated meta-analysis

XU Zhang, X Yang, M Wang, X Li, Q Xia, S Xu… - Rheumatology …, 2016 - Springer
The relationship between the SLC2A9 (solute carrier family 2, member 9) gene
polymorphisms and gout was still inconsistent among the individual genetic association …

The renal urate transporter SLC17A1 locus: confirmation of association with gout

JE Hollis-Moffatt, AJ Phipps-Green, B Chapman… - Arthritis research & …, 2012 - Springer
Introduction Two major gout-causing genes have been identified, the urate transport genes
SLC2A9 and ABCG2. Variation within the SLC17A1 locus, which encodes sodium …