[HTML][HTML] Effects of SARS-CoV-2 on cardiovascular system: the dual role of angiotensin-converting enzyme 2 (ACE2) as the virus receptor and homeostasis regulator …

A Aleksova, G Gagno, G Sinagra, AP Beltrami… - International journal of …, 2021 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is the entry receptor for severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), the cause of Coronavirus Disease-2019 (COVID …

Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety

S Akhtar, IF Benter, MI Danjuma, SAR Doi… - Journal of Drug …, 2020 - Taylor & Francis
The COVID-19 pandemic is caused by the severe acute-respiratory-syndrome-coronavirus-2
that uses ACE2 as its receptor. Drugs that raise serum/tissue ACE2 levels include ACE …

[HTML][HTML] Potential differential effects of renin-angiotensin system inhibitors on SARS-CoV-2 infection and lung injury in COVID-19

M Furuhashi, N Moniwa, H Takizawa, N Ura… - Hypertension …, 2020 - nature.com
Since the beginning of the twenty-first century, epidemic outbreaks of deadly pneumonia
have been caused by three coronaviruses: severe acute respiratory syndrome (SARS) …

[HTML][HTML] COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease

R Gan, NP Rosoman, DJE Henshaw, EP Noble… - Medical hypotheses, 2020 - Elsevier
Abstract SARS-CoV-2, the agent of COVID-19, shares a lineage with SARS-CoV-1, and a
common fatal pulmonary profile but with striking differences in presentation, clinical course …

[HTML][HTML] COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

M Nishiga, DW Wang, Y Han, DB Lewis… - Nature Reviews …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by a strain of coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …

Cardiology and COVID-19

RO Bonow, PT O'Gara, CW Yancy - Jama, 2020 - jamanetwork.com
The initial reports on the epidemiology of coronavirus disease 2019 (COVID-19) emanating
from Wuhan, China, offered an ominous forewarning of the risks of severe complications in …

[HTML][HTML] Renin-angiotensin system and Coronavirus disease 2019: A narrative review

A Mascolo, C Scavone, C Rafaniello… - Frontiers in …, 2020 - frontiersin.org
Although clinical manifestations of the 2019 novel coronavirus disease pandemic (COVID-
19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) …

The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2

L Chen, X Li, M Chen, Y Feng… - Cardiovascular research, 2020 - academic.oup.com
A new type of pneumonia caused by a novel coronavirus SARS-CoV-2 outbreaks recently in
China and spreads into many other countries. This disease, named as COVID-19, is similar …

[HTML][HTML] The SARS-CoV-2 receptor, ACE-2, is expressed on many different cell types: implications for ACE-inhibitor-and angiotensin II receptor blocker-based …

A Albini, G Di Guardo, DMC Noonan… - Internal and emergency …, 2020 - Springer
SARS-CoV-2 is characterized by a spike protein allowing viral binding to the angiotensin-
converting enzyme (ACE)-2, which acts as a viral receptor and is expressed on the surface …

[HTML][HTML] Circulating plasma levels of angiotensin II and aldosterone in patients with coronavirus disease 2019 (COVID-19): a preliminary report

BM Henry, S Benoit, G Lippi, J Benoit - Progress in cardiovascular …, 2020 - ncbi.nlm.nih.gov
Since angiotensin converting enzyme 2 (ACE2) was identified as the host receptor for
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), speculation has arisen …