Osteoarthritis (OA) is a low‑grade, nonspecific inflammatory disease that affects the entire
joint. This condition is characterized by synovitis, cartilage erosion, subchondral bone …

Osteoarthritis (OA), the commonest arthritis, is characterized by the progressive destruction
of cartilage, leading to disability. The Current early clinical treatment strategy for OA often …

Osteoarthritis (OA) is a joint disorder involving cartilage degeneration and subchondral bone
sclerosis. The bone-cartilage interface is implicated in OA pathogenesis due to its …

Osteoarthritis (OA) is the most common form of joint disease. Histopathologically, OA is
characterized by a progressive loss of articular cartilage, osteophyte formation, thickening of …

Chondrocytes serve diverse functions during development and postnatal life and are the
single cellular component of the articular cartilage of diarthrodial joints. During skeletal …

We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the
most widespread arthritis in the world, using the powerful tool of single-cell RNA …

Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

There is now general agreement that osteoarthritis (OA) involves all structures in the affected
joint, culminating in the degradation of the articular cartilage. It is appropriate to focus …

It is increasingly recognized that the pathogenesis of cartilage degradation in osteoarthritis
(OA) is multifactorial and involves the interactions between cartilage and its surrounding …

The synovium constitutes the envelope of articular joints and is a critical provider of synovial
fluid components and articular cartilage nutrients. Its inflammation is a predominant feature …