Highlights•Osteoarthritis (OA) is a common and debilitating disease with no effective
treatments.•Articular chondrocyte behavior and matrix maintenance are major targets.•The …

Osteoarthritis (OA) of the knee is a wide-spread, debilitating disease that is prominent in
Western countries. It is associated with old age, obesity, and mechanical stress on the knee …

The synovial tissue is an immunologically challenging environment where, under
homeostatic conditions, highly specialized subsets of immune-regulatory macrophages and …

Arthritis is inflammation of the joints accompanied by osteochondral destruction. It can take
many forms, including osteoarthritis, rheumatoid arthritis, and psoriatic arthritis. These …

Osteoarthritis (OA) is the most common cause of disability in worldwide population, which is
characterized by cartilage breakdown, synovial fibrosis, osteophyte formation and pain …

Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …

Osteoarthritis (OA) is a disease of an entire synovial joint characterized by clinical symptoms
and distortion of joint tissues, including cartilage, muscles, ligaments, and bone. Although …

Although osteoarthritis (OA) was historically referred to as the non-inflammatory arthritis, it is
now considered a condition involving persistent low-grade inflammation and activation of …

Osteoarthritis (OA) is associated with cartilage degeneration and an accompanying
inflammatory syndrome of the synovium in addition to alteration of the subchondral bone …

Osteoarthritis is the most prevalent degenerative joint disease and one of the leading
causes of physical impairment in the world's aging population. The human lifespan has …