Background Osteoarthritis (OA) is the most prevalent degenerative joint disease. In vitro
experiments are an intuitive method used to investigate its early pathogenesis. Chondrocyte …

Objective Osteoarthritis (OA) is a degenerative joint disease associated with excessive
mechanical loading. The aim here was to elucidate whether different subpopulations of …

Osteoarthritis (OA) is a leading cause of disability, globally. Despite an emerging role for
synovial inflammation in OA pathogenesis, attempts to target inflammation therapeutically …

The role of human chondrocytes in the pathogenesis of cartilage degradation in rheumatic
joint diseases has presently gained increasing interest. An active chondrocyte participation …

Osteoarthritis (OA) is a joint disease that involves degeneration of articular cartilage,
weakening of the subchondral bone and limited intra-articular inflammation manifested by …

Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …

Osteoarthritis (OA) is a chronic arthritic disease characterized by cartilage degradation,
synovial inflammation, and subchondral bone lesions. The studies on the pathogenesis of …

Osteoarthritis (OA) is the most common joint disease affecting approximately 10% of men
and 18% of women older than 60. Its pathogenesis is still not fully understood; however …

Osteoarthritis (OA) is the most common articular disease in adults and has a current
prevalence of 12% in the population over 65 years old. This chronic disease causes …

Purpose: The goal of our stduy was to use single-cell transcriptomic analysis to
systematically identify the molecular census of cell types and cell states within osteoarthritic …