Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …

Because there currently is no treatment for spinal cord injury, most patients are living with
long-standing injuries. Therefore, strategies aimed at promoting restoration of function to the …

The outcome of spinal cord injury depends on the extent of secondary damage produced by
a series of cellular and molecular events initiated by the primary trauma. This article reviews …

Despite advances in promoting axonal regeneration after acute spinal cord injury (SCI),
elicitation of bridging axon regeneration after chronic SCI remains a formidable challenge …

Background Chondroitin sulfate proteoglycan (CSPG) is a major component of the glial scar.
It is considered to be a major obstacle for central nervous system (CNS) recovery after injury …

Glial scarring following severe tissue damage and inflammation after spinal cord injury (SCI)
is due to an extreme, uncontrolled form of reactive astrogliosis that typically occurs around …

Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

Study Design. Retrospective review of current literature regarding neuroprotection and
axonal regeneration therapies for acute spinal cord injury. Objectives. To provide an update …

Spinal cord injury (SCI) research is a very complex field lending to why reviews of SCI
literatures can be beneficial to current and future researchers. This review focuses on recent …

The past 20 years has seen the emergence of many exciting and promising experimental
therapeutic strategies to promote regeneration of the injured spinal cord in laboratory …