BACKGROUND: Older adults, especially those over 65 years, are at risk of more severe
morbidity from diphtheria, tetanus and pertussis and may transmit pertussis to unvaccinated …

BACKGROUND: Pertussis can cause significant morbidity in elderly patients, who can also
transmit this disease to infants and young children. There is little data available on the use of …

BACKGROUND: Annual influenza vaccination provides an opportunity to administer a
booster dose of diphtheria, tetanus, acellular pertussis and inactivated poliomyelitis vaccine …

Reduced-antigen-content diphtheria–tetanus–acellular-pertussis (dTpa) vaccines are
predominantly recommended for once-in-a-lifetime use. A second dTpa (Boostrix™ …

Introduction: Older children and adults, susceptible to pertussis because of waning
immunity, may serve as a reservoir of infection, leading to severe disease among young …

Boostrix® is a three-pertussis component, combined, reduced-antigen content tetanus,
diphtheria, and acellular pertussis (Tdap) booster vaccine administered as a single …

Many countries recommend diphtheria, tetanus and/or poliomyelitis boosters in adolescents
or adults and the need for pertussis booster vaccination beyond childhood is increasingly …

Introduction The immunogenicity and safety of one dose of Tdap-IPV (tetanus, diphtheria,
acellular pertussis and inactivated poliomyelitis vaccine) and two doses of Td-IPV (tetanus …

Background. Booster vaccination against tetanus and diphtheria at 10-year intervals is
commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and …

At 60 months post-vaccination, adults (mean age 45.6 years) randomised to receive
combined reduced-antigen-content diphtheria–tetanus and acellular pertussis vaccine …