The comparative effects of the once a day calcium channel antagonists amlodipine and long-
acting diltiazem were assessed in a parallel design, investigator-blinded, multicenter trial in …

Thirty patients (17 females, median age 55 years) with mild/moderate hypertension (sitting
diastolic blood pressure 95-110 mmHg over 2 consecutive weeks) participated in a study of …

To determine the dose-response efficacy of once-daily administration of placebo or a new
long-acting calcium channel blocker amlodipine in patients with mild to moderate …

The antihypertensive efficacy and safety of amlodipine was evaluated in an open,
multicenter general practice study. Hypertensive patients with sitting diastolic blood pressure …

Amlodipine is a new long-acting calcium antagonist that has a long half-life and appears to
be suitable for once-daily administration. A double-blind, randomized, parallel, placebo …

Once-daily administration of amlodipine, a long-acting dihydropyridine calcium-channel
blocker, and atenolol, a cardioselective [beta]-adrenoceptor blocking agent, were compared …

The daily administration of 240 to 360 mg of diltiazem lowered blood pressure in a dose-
related pattern similar to that seen in patients taking a daily dosage of 50 to 100 mg of …

A multicenter, randomized, placebo-controlled, parallel group study of diltiazem in essential
hypertension was carried out in 77 patients (40 difazem, 37 placebo) with stable supine …

The antihypertensive efficacy and tolerability of a calcium antagonist drug, dilitiazem (60 mg
qid per os), was compared with that of metoprolol (100 mg bid per os) in a crossover, double …

Amlodipine, a new long-acting dihydropyridine calcium antagonist, was compared with
placebo and atenolol in 125 patients with mild to moderate systemic hypertension [supine …