[HTML][HTML] Autophagy modulation as a target for anticancer drug discovery
X Li, H Xu, Y Liu, N An, S Zhao, J Bao - Acta Pharmacologica Sinica, 2013 - nature.com
Autophagy, an evolutionarily conserved catabolic process involving the engulfment and
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
[HTML][HTML] Autophagy and cancer
KS Choi - Experimental & molecular medicine, 2012 - nature.com
Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic
integrity by degrading aged or malfunctioning organelles and damaged or misfolded …
integrity by degrading aged or malfunctioning organelles and damaged or misfolded …
Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients
JM Mulcahy Levy, A Thorburn - Cell Death & Differentiation, 2020 - nature.com
Autophagy allows for cellular material to be delivered to lysosomes for degradation resulting
in basal or stress-induced turnover of cell components that provide energy and …
in basal or stress-induced turnover of cell components that provide energy and …
The role of autophagy in cancer
N Santana-Codina, JD Mancias… - Annual Review of …, 2017 - annualreviews.org
Autophagy is a highly conserved and regulated process that targets proteins and damaged
organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and …
organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and …
Autophagy in tumor suppression and cancer therapy
CP Kung, A Budina, G Balaburski… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Autophagy is a stress-induced cell survival program whereby cells under metabolic,
proteotoxic, or other stress remove dysfunctional organelles and/or misfolded …
proteotoxic, or other stress remove dysfunctional organelles and/or misfolded …
Autophagy and tumorigenesis
M Rangel, J Kong, V Bhatt, K Khayati… - The FEBS …, 2022 - Wiley Online Library
Autophagy is a catabolic process that captures cellular waste and degrades them in the
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …
[HTML][HTML] Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer
B Liu, X Wen, Y Cheng - Cell death & disease, 2013 - nature.com
Autophagy (macroautophagy) is an evolutionarily conserved lysosomal degradation
process, in which a cell degrades long-lived proteins and damaged organelles. Recently …
process, in which a cell degrades long-lived proteins and damaged organelles. Recently …
[HTML][HTML] Autophagy function and dysfunction: potential drugs as anti-cancer therapy
F Cuomo, L Altucci, G Cobellis - Cancers, 2019 - mdpi.com
Autophagy is a highly conserved catabolic and energy-generating process that facilitates the
degradation of damaged organelles or intracellular components, providing cells with …
degradation of damaged organelles or intracellular components, providing cells with …
Autophagy paradox of cancer: Role, regulation, and duality
AK Verma, PS Bharti, S Rafat, D Bhatt… - Oxidative Medicine …, 2021 - Wiley Online Library
Autophagy, a catabolic process, degrades damaged and defective cellular materials through
lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily …
lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily …
[HTML][HTML] Autophagy and cancer: Basic mechanisms and inhibitor development
Y Hama, Y Ogasawara, NN Noda - Cancer Science, 2023 - ncbi.nlm.nih.gov
Autophagy is a lysosomal degradation system of cytoplasmic components that contributes to
cellular homeostasis through the turnover of various biomolecules and organelles, often in a …
cellular homeostasis through the turnover of various biomolecules and organelles, often in a …