Characterization and classification of human zona pellucida glycoproteins is essential to
understand the functions of these components during fertilization. To achieve this …

The zona pellucida (ZP), the extracellular glycocalyx that surrounds the oocyte, is well
known to mediate homologous gamete interaction. In a previous study from our laboratories …

Partial clones for the three cynomolgus monkey (Macaca fasicularis) zona pellucida genes
(cmZPA, cmZPB, and cmZPC) have previously been isolated. These partial clones …

Polyclonal antibodies were raised in mice by immunization with solubilized human zonae
pellucidae (ZP). Dot-blot analysis and ELISAs showed very strong immunoreactivity against …

A translucent matrix termed the zona pellucida (ZP) surrounds the mammalian oocyte. It
plays a critical role in fertilization by acting as a" docking site" for binding of spermatozoa …

BACKGROUND Fertilization starts with the binding of the spermatozoa to the zona pellucida
(ZP) of the oocyte. Such binding is a carbohydrate-mediated event and consists of a series …

The mammalian zona pellucida (ZP) consists of three glycoproteins (ZP1, ZP2 and ZP3),
which are variably conserved among species at the genomic and amino acid levels. In order …

BACKGROUND: The zona pellucida (ZP) is an extracellular glycoprotein matrix which
surrounds all mammalian oocytes. Recent data have shown the presence of four human …

Recent studies document that the zona pellucida matrix of human oocytes is composed of
four glycoproteins designated as ZP1, ZP2, ZP3, and ZP4 instead of three as proposed in …

Immunocontraception using the glycoproteins of the mammalian zona pellucida (ZP) has
held great promise because antibodies specific to ZP antigens would inhibit fertility and not …