Background: Considerable research has been conducted into the nature of airway
inflammation in chronic obstructive pulmonary disease (COPD) but the relationship between …

Background: COPD is an inflammatory disorder characterised by chronic airflow limitation,
but the extent to which airway inflammation is related to functional abnormalities is still …

BACKGROUND Inflammatory changes in the airways in chronic obstructive pulmonary
disease (COPD) are largely attributed to smoking, yet they may be present even if patients …

Chronic obstructive pulmonary disease (COPD) is defined by progressive, irreversible
airflow limitation and an inflammatory response of the lungs, usually to cigarette smoke …

The lung pathology of severe chronic obstructive pulmonary disease (COPD) has been
poorly investigated. We examined surgical specimens obtained from patients with severe …

Background: The predominant emphysema phenotype is associated with more severe
airflow limitation in patients with chronic obstructive pulmonary disease (COPD). A study …

The pathological hallmarks of chronic obstructive pulmonary disease (COPD) are
inflammation of the small airways (bronchiolitis) and destruction of lung parenchyma …

BACKGROUND Patients with more frequent exacerbations of chronic obstructive pulmonary
disease (COPD) may have increased bronchial inflammation. Airway inflammation was …

Background and objective: COPD is associated not only with an abnormal inflammatory
response in the lung but also with systemic inflammation, including systemic oxidative …

Study objective To assess the characteristics of airway inflammation in patients with COPD.
Methods We measured the sputum concentration of interleukin-8 (IL-8), a chemokine …