Neural correlates of polygenic risk score for autism spectrum disorders in general population

B Khundrakpam, U Vainik, J Gong… - Brain …, 2020 - academic.oup.com
Autism spectrum disorder is a highly prevalent and highly heritable neurodevelopmental
condition, but studies have mostly taken traditional categorical diagnosis approach (yes/no …

[HTML][HTML] Are autistic traits in the general population related to global and regional brain differences?

PCMP Koolschijn, HM Geurts, AR Van Der Leij… - Journal of autism and …, 2015 - Springer
There is accumulating evidence that autistic-related traits in the general population lie on a
continuum, with autism spectrum disorders representing the extreme end of this distribution …

Brain morphology, autistic traits, and polygenic risk for autism: A p opulation‐based neuroimaging study

S Alemany, E Blok, PR Jansen, RL Muetzel… - Autism …, 2021 - Wiley Online Library
Autism spectrum disorders (ASD) are associated with widespread brain alterations. Previous
research in our group linked autistic traits with altered gyrification, but without pronounced …

[HTML][HTML] Fractionating autism based on neuroanatomical normative modeling

M Zabihi, DL Floris, SM Kia, T Wolfers… - Translational …, 2020 - nature.com
Autism is a complex neurodevelopmental condition with substantial phenotypic, biological,
and etiologic heterogeneity. It remains a challenge to identify biomarkers to stratify autism …

[HTML][HTML] Atypical brain structures as a function of gray matter volume (GMV) and gray matter density (GMD) in young adults relating to autism spectrum traits

Y Yaxu, Z Ren, J Ward, Q Jiang - Frontiers in Psychology, 2020 - frontiersin.org
Individuals with autistic traits are those who present in the normal population with
characteristics of social, communication, personality, and cognitive impairments but do not …

[HTML][HTML] Decreased grey matter volumes in unaffected mothers of individuals with autism spectrum disorder reflect the broader autism endophenotype

K An, T Ikeda, T Hirosawa, K Yaoi, Y Yoshimura… - Scientific Reports, 2021 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with an early onset and a
strong genetic origin. Unaffected relatives may present similar but subthreshold …

Brain gray matter alterations and associated demographic profiles in adults with autism spectrum disorder: A meta-analysis of voxel-based morphometry studies

X Yang, T Si, Q Gong, L Qiu, Z Jia… - Australian & New …, 2016 - journals.sagepub.com
Background: There is increasing evidence that children with autism spectrum disorder are
accompanied by specific anatomical alterations. However, the anatomical abnormalities in …

Cortical surface architecture endophenotype and correlates of clinical diagnosis of autism spectrum disorder

B Yamagata, T Itahashi, J Fujino, H Ohta… - Psychiatry and …, 2019 - Wiley Online Library
Aim Prior structural magnetic resonance imaging studies demonstrated atypical gray matter
characteristics in siblings of individuals with autism spectrum disorder (ASD). However, they …

Three shades of grey: Detecting brain abnormalities in children with autism using source‐, voxel‐and surface‐based morphometry

E Pappaianni, R Siugzdaite, S Vettori… - European Journal of …, 2018 - Wiley Online Library
Autistic spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social interactions, communication and stereotyped behaviour. Recent evidence from …

Cortical and subcortical brain morphometry differences between patients with autism spectrum disorder and healthy individuals across the lifespan: results from the …

D Van Rooij, E Anagnostou, C Arango… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Neuroimaging studies show structural differences in both cortical and subcortical
brain regions in children and adults with autism spectrum disorder (ASD) compared with …