Therapeutic agents that block the calcitonin gene–related peptide (CGRP) signaling
pathway are a highly anticipated and promising new drug class for migraine therapy …

A growing body of evidence has implicated the calcitonin gene–related peptide (CGRP)
receptors in migraine pathophysiology. With the approval of monoclonal antibodies targeting …

Calcitonin gene-related peptide (CGRP) has long been hypothesized to play a key role in
migraine pathophysiology, and the advent of small-molecule antagonists has clearly …

Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …

Migraine is a common neurological disorder that is associated with an increase in plasma
calcitonin gene-related peptide (CGRP) levels. CGRP, a neuropeptide released from …

Objective To summarize the pharmacology of the calcitonin peptide family of receptors and
explore their relationship to migraine and current migraine therapies. Background …

Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …

Calcitonin gene-related peptide (CGRP), a neuropeptide abundant in the trigeminal system
and widely expressed in both the peripheral and central nervous systems, has recently …

Calcitonin gene-related peptide (CGRP) is a potent neuromodulator and vasodilator. It has
been implicated in the pathogenesis of migraine by a number of lines of evidence, although …