[HTML][HTML] Quercetin: a molecule of great biochemical and clinical value and its beneficial effect on diabetes and cancer

AS Michala, A Pritsa - Diseases, 2022 - mdpi.com
Quercetin belongs to the broader category of polyphenols. It is found, in particular, among
the flavonols, and along with kaempferol, myricetin and isorhamnetin, it is recognized as a …

The flavonoid quercetin inhibits proinflammatory cytokine (tumor necrosis factor alpha) gene expression in normal peripheral blood mononuclear cells via modulation …

MP Nair, S Mahajan, JL Reynolds… - Clinical and vaccine …, 2006 - Am Soc Microbiol
The flavonoids comprise a large class of low-molecular-weight plant metabolites
ubiquitously distributed in food plants. These dietary antioxidants exert significant antitumor …

[HTML][HTML] Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet

S Tan, JA Caparros-Martin, VB Matthews, H Koch… - Scientific Reports, 2018 - nature.com
Dietary fibre positively influences gut microbiome composition, enhancing the metabolism of
dietary flavonoids to produce bioactive metabolites. These synergistic activities facilitate the …

[HTML][HTML] A comprehensive view on the quercetin impact on colorectal cancer

AA Neamtu, TA Maghiar, A Alaya, NK Olah, V Turcus… - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) represents the third type of cancer in incidence and second in
mortality worldwide, with the newly diagnosed case number on the rise. Among the …

Quercetin protects against atherosclerosis by inhibiting dendritic cell activation

W Lin, W Wang, D Wang, W Ling - Molecular Nutrition & Food …, 2017 - Wiley Online Library
Scope Quercetin is a typical flavonol with atheroprotective effects, but the effect of quercetin
on dendritic cell (DC) maturation in relation to atherosclerosis has not yet been clearly …

Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western‐style diet in C57/BL6J mice

M Kobori, S Masumoto, Y Akimoto… - Molecular nutrition & …, 2011 - Wiley Online Library
Scope: To determine the effect of consumption of a quercetin‐rich diet on obesity and
dysregulated hepatic gene expression. Methods and results: C56BL/6J mice were fed for 20 …

Quercetin as an innovative therapeutic tool for cancer chemoprevention: Molecular mechanisms and implications in human health

RA Rather, M Bhagat - Cancer medicine, 2020 - Wiley Online Library
Cancer is a life‐threatening disease afflicting human health worldwide. Recent advances in
drug discovery infrastructure and molecular approaches have helped a lot in identifying the …

Role of flavonoids in management of inflammatory disorders

R Shukla, V Pandey, GP Vadnere, S Lodhi - Bioactive food as dietary …, 2019 - Elsevier
Flavonoids are a wide category of polyphenolic compounds that have a major role in the
treatment of various inflammatory diseases, including arthritis, gastritis, nephritis, hepatitis …

[HTML][HTML] Quercetin inhibits left ventricular hypertrophy in spontaneously hypertensive rats and inhibits angiotensin II-induced H9C2 cells hypertrophy by enhancing …

L Yan, JD Zhang, B Wang, YJ Lv, H Jiang, GL Liu… - PLoS …, 2013 - journals.plos.org
Background Quercetin is the most abundant flavonoid in fruit and vegetables and is believed
to attenuate cardiovascular disease. We hypothesized that quercetin inhibits cardiac …

Advance on the absorption, metabolism, and efficacy exertion of quercetin and its important derivatives: absorption, metabolism and function of quercetin

Y Hai, Y Zhang, Y Liang, X Ma, X Qi, J Xiao… - Food …, 2020 - Wiley Online Library
Quercetin, a dietary flavonol, has been used as potential ingredient in food supplements to
promote health. Its health effects are closely related to its bioavailability and further depend …