Histopathological evaluation of liver fibrosis: quantitative image analysis vs semi-quantitative scores: comparison with serum markers

C Pilette, MC Rousselet, P Bedossa, D Chappard… - Journal of …, 1998 - Elsevier
Background/Aims: Liver fibrosis is mainly evaluated by qualitative histological examination.
Although histological semi-quantitative scores and quantitative determination with image …

Automatic quantification of liver fibrosis: design and validation of a new image analysis method: comparison with semi-quantitative indexes of fibrosis

M Masseroli, T Caballero, F O'Valle, RMG Del Moral… - Journal of …, 2000 - Elsevier
Background/Aims: Liver fibrosis is one of the most important and characteristic histologic
alterations in progressive and chronic liver diseases. Thus, in both clinical and experimental …

A histological semiquantitative scoring system for evaluation of hepatic fibrosis in needle liver biopsy specimens: comparison with morphometric studies

M Chevallier, S Guerret, P Chossegros, F Gerard… - Hepatology, 1994 - journals.lww.com
The evaluation of hepatic fibrosis on histological sections is of great interest for the staging
and follow–up of chronic liver disease. Because no reliable scoring system is yet available …

Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis

M Friedrich-Rust, W Rosenberg, J Parkes… - BMC …, 2010 - Springer
Background FibroTest (FT) is the most frequently used serum fibrosis marker and consists of
an algorithm of five fibrosis markers (alfa2-macroglobulin, apolipoproteinA1, haptoglobin …

Assessment of fibrosis and cirrhosis in liver biopsies: an update

G Germani, P Hytiroglou, A Fotiadu… - Seminars in liver …, 2011 - thieme-connect.com
The liver biopsy specimen represents valuable material for the assessment of fibrosis and
cirrhosis. Despite limitations related to sampling and interpretation, histologic examination …

Interobserver variability in histologic evaluation of liver fibrosis using categorical and quantitative scores

M Pavlides, J Birks, E Fryer, D Delaney… - American journal of …, 2017 - academic.oup.com
Objectives: The aim of the study was to investigate the interobserver agreement for
categorical and quantitative scores of liver fibrosis. Methods: Sixty-five consecutive biopsy …

Noninvasive diagnosis of fibrosis in chronic liver disease

R Lichtinghagen, MJ Bahr - Expert review of molecular diagnostics, 2004 - Taylor & Francis
Laboratory tests for the noninvasive diagnosis of liver fibrosis were studied extensively in the
past. However, no test is yet accepted to replace liver biopsy as the gold standard. The …

Quantitative versus morphological assessment of liver fibrosis: semi‐quantitative scores are more robust than digital image fibrosis area estimation

M Wright, M Thursz, R Pullen, H Thomas… - Liver …, 2003 - Wiley Online Library
Background/Aim: Digital image analysis (DIA) allows quantitative assessment of fibrosis on
liver biopsy. Accurate determination of a threshold greyscale level representing fibrous …

[HTML][HTML] Evaluation of liver fibrosis:“Something old, something new…”

Z Almpanis, M Demonakou… - Annals of gastroenterology …, 2016 - ncbi.nlm.nih.gov
Hepatic fibrogenesis may gradually result to cirrhosis due to the accumulation of
extracellular matrix components as a response to liver injury. Thus, therapeutic decisions in …

Regression of liver fibrosis: evidence and challenges

YM Sun, SY Chen, H You - Chinese Medical Journal, 2020 - mednexus.org
It has been reported that liver fibrosis could be reversed after eliminating liver injuries. This
article systematically summarizes the evidence of fibrosis regression based on histology …