Alkaloids for cancer prevention and therapy: Current progress and future perspectives

A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …

[HTML][HTML] Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

P Dhyani, C Quispe, E Sharma, A Bahukhandi… - Cancer cell …, 2022 - Springer
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …

[HTML][HTML] Alkaloids isolated from natural herbs as the anticancer agents

JJ Lu, JL Bao, XP Chen, M Huang… - … and alternative medicine …, 2012 - ncbi.nlm.nih.gov
Alkaloids are important chemical compounds that serve as a rich reservoir for drug
discovery. Several alkaloids isolated from natural herbs exhibit antiproliferation and …

Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology

T Efferth, F Oesch - Seminars in Cancer Biology, 2021 - Elsevier
Drug repurposing (or repositioning) is an emerging concept to use old drugs for new
treatment indications. Phytochemicals isolated from medicinal plants have been largely …

[HTML][HTML] Anticancer alkaloids from trees: Development into drugs

T Isah - Pharmacognosy reviews, 2016 - ncbi.nlm.nih.gov
Trees have made an enormous phytochemical contribution in anticancer drugs'
development more than any other life form. The contributions include alkaloids that are …

Natural alkaloids: basic aspects, biological roles, and future perspectives

QIU Shi, SUN Hui, AH Zhang, XU Hong-Ying… - Chinese Journal of …, 2014 - Elsevier
Natural products have gained popularity worldwide for promoting healthcare, as well as
disease prevention. Alkaloids are important chemical compounds that serve as a rich …

[PDF][PDF] Alkaloids-important therapeutic secondary metabolites of plant origin

R Kaur, S Arora - J Crit Rev, 2015 - e-tarjome.com
Plants are eminent source of new therapeutic agents that helps to alleviate human ailments
and promote health. The noteworthy preventive and protective properties of these …

[HTML][HTML] Emerging cytotoxic alkaloids in the battle against cancer: Overview of molecular mechanisms

Z Habli, G Toumieh, M Fatfat, ON Rahal… - Molecules, 2017 - mdpi.com
Considered as the second deadliest disease globally, cancer has captured the attention of
researchers who have been trying with perseverance to decode its hidden aspects, to find …

[HTML][HTML] Update and new insights on future cancer drug candidates from plant-based alkaloids

M Tilaoui, H Ait Mouse, A Zyad - Frontiers in Pharmacology, 2021 - frontiersin.org
Cancer is a complex multifactorial disease that results from alterations in many physiological
and biochemical functions. Over the last few decades, it has become clear that cancer cells …

[HTML][HTML] Therapeutic role of alkaloids and alkaloid derivatives in cancer management

K Olofinsan, H Abrahamse, BP George - Molecules, 2023 - mdpi.com
Cancer is a neoplastic disease that remains a global challenge with a reported prevalence
that is increasing annually. Though existing drugs can be applied as single or combined …