Natural killer (NK) cell-mediated cytotoxicity is triggered by multiple activating receptors
associated with the signaling adaptor protein DNAX activation protein 12/killer cell-activating …

Natural killer (NK) cells express an array of activating receptors that associate with DAP12
(KARAP), CD3ζ, and/or FcRγ ITAM (immunoreceptor tyrosine-based activation motif) …

Stimulatory killer Ig-like receptors (KIRs) are expressed by various lymphocytes, including
NK cells and subsets of T cells. In NK cells, KIRs associate with the adapter molecule …

Surface receptors involved in natural killer (NK) cell triggering during the process of tumor
cell lysis have recently been identified. Of these receptors, NKp44 is selectively expressed …

After culture in interleukin (IL)-2, natural killer (NK) cells acquire an increased capability of
mediating non–major histocompatibility complex (MHC)–restricted tumor cell lysis. This may …

Activated NK cells lyse tumor cells and virus-infected cells and produce IFN-γ upon contact
with sensitive target cells. The regulation of these effector responses in resting NK cells is …

Receptors encoded by the natural killer (NK) cell gene complex (such as NKG2D) govern
the reactivity of NK cells. However, the function and ligand (s) of the NK cell gene complex …

Natural killer (NK) cell cytotoxicity is mediated by multiple germ line‐encoded activating
receptors that recognize specific ligands expressed by tumor cells and virally infected cells …

In myeloid dendritic cells (mDCs), TLR3 is expressed in the endosomal membrane and
interacts with the adaptor toll/interleukin 1 receptor homology domain–containing adaptor …

Natural killer (NK) cell sense virally infected cells and tumor cells through multiple cell
surface receptors. Many NK cell–activating receptors signal through immunoreceptor …